Robert A. Gatenby

The Hallmarks of Cancer as Eco-Evolutionary Processes

Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma

A gene for all seasons: The evolutionary consequences of HIF-1 in carcinogenesis, tumor growth and metastasis

Updating the Definition of Cancer

Evolution-based mathematical models significantly prolong response to abiraterone in metastatic castrate-resistant prostate cancer and identify strategies to further improve outcomes

Coupled Source-Sink Habitats Produce Spatial and Temporal Variation of Cancer Cell Molecular Properties as an Alternative to Branched Clonal Evolution and Stem Cell Paradigms

Dynamic super-enhancer core regulatory circuits and epigenetic landscapes drive malignant progression and refractory disease in multiple myeloma

Integrating evolutionary dynamics into cancer therapy

Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer

Mutation–selection balance and compensatory mechanisms in tumour evolution

An evolutionary framework for treating pediatric sarcomas

Leveraging transcriptional dynamics to improve BRAF inhibitor responses in melanoma

Signal transmission through elements of the cytoskeleton form an optimized information network in eukaryotic cells

Ion-Based Cellular Signal Transmission, Principles of Minimum Information Loss, and Evolution by Natural Selection

Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer

Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer

Classifying the evolutionary and ecological features of neoplasms

The Warburg effect as an adaptation of cancer cells to rapid fluctuations in energy demand

Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution

Spatial vs. non-spatial eco-evolutionary dynamics in a tumor growth model

Cellular information dynamics through transmembrane flow of ions

Coevolution of Tumor Cells and Their Microenvironment: “Niche Construction in Cancer”

Darwinian Dynamics of Intratumoral Heterogeneity: Not Solely Random Mutations but Also Variable Environmental Selection Forces

Aggregation Effects and Population-Based Dynamics as a Source of Therapy Resistance in Cancer

Quantitative Computed Tomographic Descriptors Associate Tumor Shape Complexity and Intratumor Heterogeneity with Prognosis in Lung Adenocarcinoma

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302

Ancient hot and cold genes and chemotherapy resistance emergence

Pathology to Enhance Precision Medicine in Oncology

The multiple facets of Peto's paradox: a life-history model for the evolution of cancer suppression

Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites