Area of research
Cardiology and Cardiovascular Medicine · Genetics
Research interest
Research interests include Genetic Associations and Epidemiology, Cardiomyopathy and Myosin Studies, Lipoproteins and Cardiovascular Health, and Diabetes, Cardiovascular Risks, and Lipoproteins.
Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction
Leveraging Large-Scale Biobanks for Therapeutic Target Discovery
Proteomic Analysis of Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Clinical Trial
Quality of Life and Exercise Capacity in Early Stage and Subclinical Hypertrophic Cardiomyopathy: A Secondary Analysis of the VANISH Trial
Questão social e pandemia da Covid-19: expressões sobre a educação pública brasileira
Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure
Global distributions of age- and sex-related arterial stiffness: systematic review and meta-analysis of 167 studies with 509,743 participants
Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation–Contraction Coupling
Cardiac Remodeling in Subclinical Hypertrophic Cardiomyopathy
Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation
Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas
Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes
mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes
European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases
European Heart Rhythm Association (<scp>EHRA</scp>)/Heart Rhythm Society (<scp>HRS</scp>)/Asia Pacific Heart Rhythm Society (<scp>APHRS</scp>)/Latin American Heart Rhythm Society (<scp>LAHRS</scp>) Expert Consensus Statement on the state of genetic testing for cardiac diseases
Population Prevalence of Premature Truncating Variants in Plakophilin-2 and Association With Arrhythmogenic Right Ventricular Cardiomyopathy: A UK Biobank Analysis
Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature
Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy
Cardiovascular Health and Atrial Fibrillation or Flutter: A Cross-Sectional Study from ELSA-Brasil
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial
Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy
Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency
Discordant clinical features of identical hypertrophic cardiomyopathy twins
Genetic mechanisms of critical illness in COVID-19
Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy
A Validated Model for Sudden Cardiac Death Risk Prediction in Pediatric Hypertrophic Cardiomyopathy
Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy
Disease-specific variant pathogenicity prediction significantly improves variant interpretation in inherited cardiac conditions