Area of research
Immunology · Oncology
Research interest
Research interests include Immune Cell Function and Interaction, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, and T-cell and B-cell Immunology.
CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells
Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering
Anti–miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response
Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells
B cells and tertiary lymphoid structures promote immunotherapy response
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells
Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity