Area of research
Molecular Biology · Spectroscopy
Research interest
Research interests include Advanced NMR Techniques and Applications, Protein Structure and Dynamics, NMR spectroscopy and applications, and Computational Drug Discovery Methods.
A Phosphorylation Switch Modulates Configurational Codes in the Oncofetal IGF2BP RNA Binding Paralogs
Leveraging relaxation-optimized <sup>1</sup>H-<sup>13</sup>C<sub>F</sub> correlations in 4-<sup>19</sup>F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins.
FoxP3 forms a head-to-head dimer in vivo and stabilizes its multimerization on adjacent microsatellites
A composite motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin.
Hardness of measuring magic resource
Mechanism for controlled assembly of transcriptional condensates by Aire
Mechanism for controlled assembly of transcriptional condensates by Aire.
Protein NMR assignment by isotope pattern recognition.
Characterization of conformational states of the homodimeric enzyme fluoroacetate dehalogenase by <sup>19</sup>F-<sup>13</sup>C two-dimensional NMR.
A novel motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin
Lactate regulates cell cycle by remodelling the anaphase promoting complex
Targeting ROS production through inhibition of NADPH oxidases.
Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions.
Carrier protein mediated cargo sensing in quorum signal synthases.
Complete non-proline backbone resonance assignments of the S. aureus neutrophil serine protease inhibitor, EapH1.
Non-covalent SARS-CoV-2 M<sup>pro</sup> inhibitors developed from in silico screen hits.
Emerging frontiers in virtual drug discovery: From quantum mechanical methods to deep learning approaches
The metaphorical swiss army knife: The multitude and diverse roles of HEAT domains in eukaryotic translation initiation
PH domain-mediated autoinhibition and oncogenic activation of Akt.
The metaphorical swiss army knife: The multitude and diverse roles of HEAT domains in eukaryotic translation initiation.
<sup>15</sup>N-Detected TROSY NMR experiments to study large disordered proteins in high-field magnets.
Author response: PH domain-mediated autoinhibition and oncogenic activation of Akt
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening.
Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson’s disease
The structural basis of PTEN regulation by multi-site phosphorylation.
Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection.
A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.
VirtualFlow Ants-Ultra-Large Virtual Screenings with Artificial Intelligence Driven Docking Algorithm Based on Ant Colony Optimization.
Local Deuteration Enables NMR Observation of Methyl Groups in Proteins from Eukaryotic and Cell-Free Expression Systems.