Claudia Kemper

Complement: The Road Less Traveled

Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

Systematic single-cell pathway analysis to characterize early T cell activation

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells

LFA-1 in T cell priming, differentiation, and effector functions

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate

Complement and human T cell metabolism: Location, location, location

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

Complement in Motion: The Evolution of CD46 from a Complement Regulator to an Orchestrator of Normal Cell Physiology

Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10

Complement and the Regulation of T Cell Responses

The intestinal complement system in inflammatory bowel disease: Shaping intestinal barrier function

Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism

Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation

Keeping It All Going—Complement Meets Metabolism

Intracellular complement − the complosome − in immune cell regulation

Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development

Regulation of epithelial cell expressed C3 in the intestine – Relevance for the pathophysiology of inflammatory bowel disease?

Dysregulated CD46 shedding interferes with Th1‐contraction in systemic lupus erythematosus

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4 ⁺ T cells

Complement-Mediated Regulation of Metabolism and Basic Cellular Processes

The “ins and outs” of complement‐driven immune responses

A novel “complement–metabolism–inflammasome axis” as a key regulator of immune cell effector function

CD46 Activation Regulates miR-150–Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells

A TSLP-complement axis mediates neutrophil killing of methicillin-resistant <i>Staphylococcus aureus</i>

Graft dysfunction in chronic antibody-mediated rejection correlates with B-cell–dependent indirect antidonor alloresponses and autocrine regulation of interferon-γ production by Th1 cells

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses