Area of research
Cardiology and Cardiovascular Medicine · Physiology
Research interest
Research interests include Nitric Oxide and Endothelin Effects, Cardiovascular Function and Risk Factors, Cardiac Fibrosis and Remodeling, and Mitochondrial Function and Pathology.
Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model
SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy
Effects of Sodium‐Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice
Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis
Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload–Induced Myocardial Failure in Mice
Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases
Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease
Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity
Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease
Production of adeno-associated virus vectors for in vitro and in vivo applications
Redox Regulation <i>via</i> Glutaredoxin-1 and Protein <i>S</i> -Glutathionylation
Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease
Decreased ATP production and myocardial contractile reserve in metabolic heart disease
Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease
High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II
A Redox-resistant Sirtuin-1 Mutant Protects against Hepatic Metabolic and Oxidant Stress
Cytosolic H<sub>2</sub>O<sub>2</sub> mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload
Adiponectin Modulates Oxidative Stress-Induced Autophagy in Cardiomyocytes
Cardiovascular Redox and Ox Stress Proteomics
Long & Medium Term Research: Foraging and Sex Allocation Behavior of an Autoparasitoid in a Spatially-Structured Environment
Changing Values in Pesticide Technology
Dissertation Research: Sex Ratio in an Autoparasitoid Wasp
Ecology of the Genetic Feedback Mechanism in Parasite-Host Systems
Doctoral Dissertation Research in Ecology
Genetic Feedback Interactions in Parasite-Host Systems
Applications of Ecological Population Dynamics to the Pesticide Resistance Problem to Reduce Environmental Risks
Assessment of the Scientific and Technological Information Base For Decisions on Management of Pests Using Non-ChemicalControls
Ecology of Population Regulatory Mechanisms in Exploiter- Victim Systems
Assessment of Resource-Limited Inputs to Food Protein Production Systems
Energy/Environmental Systems: an Experiment in Multi- Disciplinary Training
Ecology of the Genetic Feedback Mechanism