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Paola Oliva

University of Ferrara · IT
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Area of research
Organic Chemistry · Physiology
Research interest
Research interests include Chemistry, Stereochemistry, Tubulin, Moiety, In vivo, and Combretastatin.
h-index
citations
481
works
23
NIH funding
primary concept
email

Recent publications

2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl)methanones as A<sub>1</sub> Adenosine Receptor Positive Allosteric Modulators
ACS Medicinal Chemistry Letters 2023cited by 1position: firstdoi
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis
European Journal of Medicinal Chemistry 2022cited by 45position: middledoi
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents
Pharmaceutics 2022cited by 18position: firstdoi
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities
Pharmaceuticals 2022cited by 14position: middledoi
Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold
International Journal of Molecular Sciences 2022cited by 12position: middledoi
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
European Journal of Medicinal Chemistry 2021cited by 19position: middledoi
Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti‑tubulin tetrahydrothieno[2,3‑c]pyridine derivative and a peptide nucleic acid targeting miR‑221‑3p
International Journal of Oncology 2021cited by 10position: middledoi
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
European Journal of Medicinal Chemistry 2020cited by 34position: firstdoi
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
Bioorganic Chemistry 2020cited by 19position: middledoi
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
Molecules 2020cited by 15position: middledoi
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents
Molecules 2020cited by 8position: firstdoi
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-<i>d</i>]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors
Journal of Medicinal Chemistry 2019cited by 46position: middledoi
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
European Journal of Medicinal Chemistry 2019cited by 36position: middledoi
3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
Bioorganic Chemistry 2018cited by 22position: middledoi
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting
Bioorganic & Medicinal Chemistry Letters 2018cited by 20position: middledoi
Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells
Journal of Enzyme Inhibition and Medicinal Chemistry 2018cited by 13position: middledoi
A2A Adenosine Receptor: Structures, Modeling, and Medicinal Chemistry
2018cited by 7position: middledoi
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents
European Journal of Medicinal Chemistry 2017cited by 33position: middledoi
Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents
Scientific Reports 2017cited by 27position: middledoi
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
European Journal of Medicinal Chemistry 2017cited by 21position: middledoi
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors
Bioorganic & Medicinal Chemistry Letters 2017cited by 16position: middledoi
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole
Scientific Reports 2016cited by 36position: middledoi
The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation
Scientific Reports 2016cited by 9position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Romeo Romagnoli · University of Ferrara19 papers (2016–2022)Giampietro Viola · University of Padua14 papers (2016–2022)Andrea Brancale · Eunice Kennedy Shriver National Institute of Child Health and Human Development13 papers (2016–2022) · 13 papers (2016–2022)Roberta Bortolozzi · University of Padua13 papers (2016–2022)Salvatore Ferla · Swansea University13 papers (2016–2022)Filippo Prencipe · University of Ferrara10 papers (2016–2022)Elena Mariotto · University of Padua9 papers (2016–2022)Pier Giovanni Baraldi · University of Ferrara8 papers (2016–2019)Stefania Baraldi · University of Ferrara8 papers (2016–2019)Stefano Manfredini · University of Ferrara7 papers (2020–2022) · 7 papers (2016–2021)María Kimatrai Salvador · University of Ferrara7 papers (2017–2021)M Cara · University of Ferrara6 papers (2016–2019)Giuseppe Basso · University of Padua5 papers (2016–2017)Sandra Liekens · KU Leuven3 papers (2017–2020)Fatlum Rruga · University of Padua3 papers (2019–2021)Roberto Gambari · University of Ferrara3 papers (2020–2022)Jan Balzarini · KU Leuven3 papers (2017–2020)Diana Corallo · University of Padua3 papers (2022–2022)
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