Area of research
Molecular Biology · Hematology
Research interest
Research interests include Acute Myeloid Leukemia Research, MicroRNA in disease regulation, Cell death mechanisms and regulation, and Melanoma and MAPK Pathways.
A STAT3 degrader demonstrates efficacy in venetoclax resistant acute myeloid leukemia.
RAS Mutation-Specific Responses to Paralog- and State-Selective RAS Inhibitors.
A molecular glue halts RAS-MAPK signaling.
Chaperone-mediated autophagy protects against retinal photoreceptor degeneration by modulating proteostasis of glucose metabolism enzymes.
Munc13-4-STX7 inhibitors impair endosomal TLR activation and systemic inflammation.
Figure S4 from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
Figure S3 from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
Figure S2 from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
Supplementary Data Legends from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
Figure S5 from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
Data from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
Figure S1 from RAS Mutation–Specific Responses to Paralog- and State-Selective RAS Inhibitors
LRP8 is a receptor for tick-borne encephalitis virus
Resistance mechanisms and therapeutic strategies of CDK4 and CDK6 kinase targeting in cancer.
Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors
Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors.
LRP8 is a receptor for tick-borne encephalitis virus.
Mechanism of dimer selectivity and binding cooperativity of BRAF inhibitors
Small molecule disruption of RARα/NCoR1 interaction inhibits chaperone-mediated autophagy in cancer.
Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity.
Mechanism of dimer selectivity and binding cooperativity of BRAF inhibitors.
Quiescent OXPHOS-High Triple-Negative Breast Cancer Cells That Persist After Chemotherapy Depend on BCL-XL for Survival.
Data from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Defective chaperone-mediated autophagy in the retinal pigment epithelium of age-related macular degeneration patients.
Supplementary Methods from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Mechanism of Dimer Selectivity and Binding Cooperativity of BRAF Inhibitors
Supplementary Table S1 from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Supplementary Table S5 from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Supplementary Table S2 from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Supplementary Table S4 from Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia