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Thaddeus J. Unger

Tagworks Pharmaceuticals (Netherlands) · NL
Area of research
Molecular Biology · Hematology
Research interest
Research interests include Nuclear Structure and Function, Multiple Myeloma Research and Treatments, PI3K/AKT/mTOR signaling in cancer, and Retinoids in leukemia and cellular processes.
h-index
20
citations
2,235
works
38
NIH funding
primary concept
email

Recent publications

Abstract PR008: MYTHIC: First-in-human (FIH) biomarker-driven phase I trial of PKMYT1 inhibitor lunresertib (lunre) alone and with ATR inhibitor camonsertib (cam) in solid tumors with <i>CCNE1</i> amplification or deleterious alterations in <i>FBXW7</i> or <i>PPP2R1A</i>
Molecular Cancer Therapeutics 2023cited by 18position: middledoi
A 2:1 randomized, open-label, phase II study of selinexor vs. physician’s choice in older patients with relapsed or refractory acute myeloid leukemia
Leukemia & lymphoma/Leukemia and lymphoma 2021cited by 22position: middledoi
Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials
Leukemia 2020cited by 86position: middledoi
Clinical Implications of Targeting XPO1-mediated Nuclear Export in Multiple Myeloma
Clinical Lymphoma Myeloma & Leukemia 2018cited by 118position: middledoi
Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin lymphoma
Blood 2017cited by 157position: middledoi
A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia
Blood 2017cited by 152position: middledoi
First-in-Class, First-in-Human Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Patients With Advanced Solid Tumors
Journal of Clinical Oncology 2016cited by 247position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sharon Shacham · Karyopharm Therapeutics (United States)3 papers (2016–2017)Tami Rashal · Cancer Clinic3 papers (2016–2017)Robert Carlson · University of Oxford3 papers (2016–2017)Nashat Gabrail · Gabrail Cancer Center3 papers (2016–2017)Michael Kauffman · University of Coimbra3 papers (2016–2017)Lynn Savoie · University of Calgary2 papers (2017–2017)Michael R. Savona · Vanderbilt University2 papers (2017–2017)Ramiro Garzon · University of Utah2 papers (2017–2017)Richard M. Stone · Harvard University2 papers (2017–2017)Rachid Baz · Moffitt Cancer Center2 papers (2017–2017)Jean-Richard Saint-Martin · Karyopharm Therapeutics (United States)2 papers (2017–2017)Martin Gutierrez · Hackensack University Medical Center2 papers (2017–2017)Fiona Simpkins · University of Pennsylvania Health System1 papers (2023–2023) · 1 papers (2017–2017)Ryan H. Moy · City University of New York1 papers (2023–2023) · 1 papers (2018–2018)Peter Martin · Griffith University1 papers (2017–2017)Dan T. Vogl · Abramson Cancer Center1 papers (2018–2018)María Koehler · Pfizer (United States)1 papers (2023–2023)Patricia LoRusso · Yale Cancer Center1 papers (2023–2023)