Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Genotoxicity, DNA damage, DNA repair, Biology, Carcinogenesis, and Micronucleus test.
Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O6-methylguanine in vivo
Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer
DNA Repair and Its Influence on Points of Departure for Alkylating Agent Genotoxicity
DNA damage and the balance between survival and death in cancer biology
Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™)
DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis
Theoretical considerations for thresholds in chemical carcinogenesis
Assessment of mechanisms driving non-linear dose–response relationships in genotoxicity testing
Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells
Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses
Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
Does increase in DNA repair allow “Tolerance‐to‐Insult” in chemical carcinogenesis? Skin tumor experiments with MGMT‐overexpressing mice
Investigating Mechanisms for Non-linear Genotoxic Responses, and Analysing Their Effects in Binary Combination