Area of research
Immunology · Infectious Diseases
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, Immune Cell Function and Interaction, SARS-CoV-2 and COVID-19 Research, and T-cell and B-cell Immunology.
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis
Molecular mimicry in multisystem inflammatory syndrome in children
Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
Germline mutations in a G protein identify signaling cross-talk in T cells
Human inherited complete STAT2 deficiency underlies inflammatory viral diseases
Type I interferon signature and cycling lymphocytes in macrophage activation syndrome
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C
NFKB2 haploinsufficiency identified via screening for IFN-α2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2–related complications
Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay
Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19
The interferon landscape along the respiratory tract impacts the severity of COVID-19
Multisystem inflammation and susceptibility to viral infections in human ZNFX1 deficiency
Distinct clinical and immunological features of SARS–CoV-2–induced multisystem inflammatory syndrome in children
Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations
Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: A working group report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology
Comprehensive Genetic Results for Primary Immunodeficiency Disorders in a Highly Consanguineous Population
Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity
Use of Genetic Testing for Primary Immunodeficiency Patients
Clinical, immunologic, and genetic spectrum of 696 patients with combined immunodeficiency
Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content
Leucine-rich repeat containing 8A (LRRC8A)–dependent volume-regulated anion channel activity is dispensable for T-cell development and function
Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation
A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency
Spectrum of Phenotypes Associated with Mutations in LRBA
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency
Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections
Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association