← back to search

Hellmut G. Augustin

Heidelberg Engineering (Germany) · DE
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Angiogenesis and VEGF in Cancer, Cancer, Hypoxia, and Metabolism, Cancer Cells and Metastasis, and Axon Guidance and Neuronal Signaling.
h-index
94
citations
29,249
works
407
NIH funding
primary concept
Biology
email

Recent publications

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance
Nature Cell Biology 2026cited by 3position: middledoi
Hepatic stellate cells control liver zonation, size and functions via R-spondin 3
Nature 2025cited by 73position: middledoi
A Unique Signature for Cancer‐Associated Fibroblasts in Melanoma Metastases
Pigment Cell & Melanoma Research 2025cited by 5position: middledoi
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms
Developmental Cell 2025cited by 5position: lastdoi
DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscape
Nucleic Acids Research 2025cited by 3position: lastdoi
A systems view of the vascular endothelium in health and disease
Cell 2024cited by 258position: firstdoi
Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency
Nature Cancer 2024cited by 34position: lastdoi
CAF Specific Expression of Podoplanin May Be Dispensable for the Malignancy of Malignant Melanoma
Molecular Carcinogenesis 2024cited by 3position: middledoi
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling
Journal of Hepatology 2023cited by 91position: middledoi
Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
Cancer Research 2023cited by 46position: middledoi
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
Nature Cardiovascular Research 2023cited by 25position: middledoi
Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression
Cancers 2023cited by 16position: middledoi
Systemic Reprogramming of Endothelial Cell Signaling in Metastasis and Cachexia
Physiology 2023cited by 13position: lastdoi
Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression
Journal of Clinical Investigation 2022cited by 105position: middledoi
Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy
Cancer Research 2022cited by 35position: lastdoi
Caspase‐8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice
EMBO Molecular Medicine 2022cited by 32position: middledoi
Primary tumor–derived systemic nANGPTL4 inhibits metastasis
The Journal of Experimental Medicine 2022cited by 26position: middledoi
Activating NO–sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury
The Journal of Experimental Medicine 2022cited by 23position: middledoi
Viewpoints: Dual-blocking antibody against VEGF-A and angiopoietin-2 for treating vascular diseases of the eye
Trends in Molecular Medicine 2022cited by 9position: middledoi
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Nature Medicine 2022cited by 7position: middledoi
Lung endothelium instructs dormancy of susceptible metastatic tumour cells
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 3position: lastdoi
Endothelial Dnmt3a controls placenta vascularization and function to support fetal growth
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 3position: middledoi
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Nature 2021cited by 1,219position: middledoi
Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells
Nature Communications 2021cited by 122position: middledoi
STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis
Science Signaling 2021cited by 118position: middledoi
A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver
Developmental Cell 2021cited by 109position: lastdoi
Angiodiversity and organotypic functions of sinusoidal endothelial cells
Angiogenesis 2021cited by 102position: lastdoi
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis
Science Translational Medicine 2021cited by 95position: lastdoi
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
Med 2021cited by 64position: middledoi
Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor–endothelial cell crosstalk
Nature Neuroscience 2021cited by 51position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Carolin Mogler · Tumaini University20 papers (2013–2025)Mahak Singhal · Max Delbrück Center17 papers (2017–2023)Junhao Hu · Northeast Petroleum University17 papers (2012–2021)Nicolas Gengenbacher · German Cancer Research Center11 papers (2017–2025)Claudia Korn · Roche (Switzerland)11 papers (2012–2019)Sergij Goerdt · Heidelberg University11 papers (2012–2022)Gou Young Koh · Korea Advanced Institute of Science and Technology10 papers (2016–2024)Eva Besemfelder · DKFZ-ZMBH Alliance10 papers (2012–2021)Soniya Savant · Karolinska Institutet9 papers (2013–2018)Ralf H. Adams · University of Oklahoma Health Sciences Center9 papers (2014–2023)Moritz Jakab · German Cancer Research Center8 papers (2020–2025)Carmen Ruiz de Almodóvar · University of Bonn8 papers (2015–2022)Ashik Ahmed Abdul Pari · DKFZ-ZMBH Alliance7 papers (2018–2022)Matthias Schlesner · University of Augsburg7 papers (2018–2025)Markus Thomas · German Cancer Research Center7 papers (2012–2020)Cyrill Géraud · University Hospital Heidelberg7 papers (2012–2020)Katharina Schlereth · German Cancer Research Center6 papers (2017–2025)Jochen Utikal · German Cancer Research Center6 papers (2018–2025)Moritz Felcht · Heidelberg University6 papers (2012–2022)Sila Appak‐Baskoy · Toronto Metropolitan University6 papers (2012–2021)