Area of research
Hematology · Genetics
Research interest
Research interests include Platelet, In vivo, Thrombin, microRNA, Receptor, and Solid tumor.
The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes
Nanomedicine platform for targeting activated neutrophils and neutrophil–platelet complexes using an α1-antitrypsin-derived peptide motif
Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand
Factor XII and uPAR upregulate neutrophil functions to influence wound healing
The protease‐activated receptor 4 Ala120Thr variant alters platelet responsiveness to low‐dose thrombin and protease‐activated receptor 4 desensitization, and is blocked by non‐competitive P2Y12 inhibition
Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth
Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets
Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race