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Jacob E. Lemieux

Broad Institute ·
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Area of research
Infectious Diseases · Parasitology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, SARS-CoV-2 detection and testing, Vector-borne infectious diseases, and COVID-19 Clinical Research Studies.
h-index
38
citations
8,906
works
139
NIH funding
primary concept
Medicine
email

Recent publications

Deep untargeted wastewater metagenomic sequencing from sewersheds across the United States
medRxiv 2026cited by 1position: middledoi
Multiplexed detection of febrile infections using CARMEN
Nature Communications 2025cited by 2position: middledoi
Persistent SARS-CoV-2 infection: significance and implications
The Lancet Infectious Diseases 2024cited by 148position: middledoi
SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency
Science Translational Medicine 2024cited by 95position: middledoi
Emerging SARS-CoV-2 Resistance After Antiviral Treatment
JAMA Network Open 2024cited by 41position: middledoi
Auto-Abs neutralizing type I IFNs in patients with severe Powassan, Usutu, or Ross River virus disease
The Journal of Experimental Medicine 2024cited by 27position: middledoi
Preliminary clinical performance of a Cas13a-based lateral flow assay for detecting <i>Neisseria gonorrhoeae</i> in urine specimens
mSphere 2024cited by 7position: lastdoi
Development of Cas13a-based assays for <i>Neisseria gonorrhoeae</i> detection and gyrase A determination
mSphere 2023cited by 24position: lastdoi
Author Correction: Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
Nature Medicine 2023cited by 2position: middledoi
Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness
Science 2022cited by 345position: lastdoi
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
Nature Medicine 2022cited by 296position: middledoi
Defining the risk of SARS-CoV-2 variants on immune protection
Nature 2022cited by 180position: middledoi
Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis
mBio 2021cited by 119position: middledoi
Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19
Journal of the Neurological Sciences 2021cited by 89position: middledoi
Transmission from vaccinated individuals in a large SARS-CoV-2 Delta variant outbreak
Cell 2021cited by 48position: middledoi
Intrathecal inflammatory responses in the absence of SARS-CoV-2 nucleic acid in the CSF of COVID-19 hospitalized patients
Journal of the Neurological Sciences 2021cited by 41position: middledoi
Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows
Nature Microbiology 2021cited by 17position: middledoi
Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: a guide and case study in setting up an emergency-use, laboratory-developed molecular microbiological assay
Journal of Clinical Pathology 2021cited by 15position: middledoi
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and SARS-CoV-2 variants
medRxiv 2021cited by 9position: middledoi
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant
Cell 2020cited by 1,118position: middledoi
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2
Nature Communications 2020cited by 504position: middledoi
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
Science 2020cited by 318position: firstdoi
Powassan Virus Neuropathology and Genomic Diversity in Patients With Fatal Encephalitis
Open Forum Infectious Diseases 2020cited by 35position: middledoi
Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing
Clinical Infectious Diseases 2017cited by 55position: middledoi
A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse
Nature Microbiology 2016cited by 108position: firstdoi
GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome
Blood 2013cited by 244position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Pardis C. Sabeti · Broad Institute12 papers (2016–2025)Gordon Adams · Broad Institute7 papers (2017–2024)Shibani S. Mukerji · Harvard University5 papers (2017–2021)Anne Piantadosi · Emory University5 papers (2017–2024)Erica Normandin · National Institutes of Health4 papers (2020–2021)John A. Branda · Harvard University4 papers (2021–2024)Eric Rosenberg · Brigham and Women's Hospital4 papers (2016–2021)Bennett Shaw · University of California System4 papers (2020–2021)Bronwyn MacInnis · Broad Institute3 papers (2020–2022)S. F. Schaffner · Augusta University3 papers (2016–2022)Lao‐Tzu Allan‐Blitz · Massachusetts Institute of Technology3 papers (2023–2025)Lisa M. Freimark · Massachusetts Institute of Technology3 papers (2016–2021)Isaac H. Solomon · Harvard University3 papers (2020–2021)Matthew P. Frosch · Harvard University3 papers (2017–2021)Siavash Zamirpour · University of California, San Francisco2 papers (2017–2020)Pritha Sen · Mass General Brigham2 papers (2021–2021)Vijay Ganesh · Georgia Institute of Technology2 papers (2017–2021)Graham McGrath · Massachusetts General Hospital2 papers (2016–2017)Leonid Yurkovetskiy · University of Massachusetts Chan Medical School2 papers (2020–2022)Tracey Cho · University of Iowa2 papers (2017–2021)
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