Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, Cancer Immunotherapy and Biomarkers, and Gene Regulatory Network Analysis.
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma
Early tolerance and late persistence as alternative drug responses in cancer
Genomic landscape of diffuse glioma revealed by whole genome sequencing
Scalable, fast and accurate differential gene expression testing from millions of cells of multiple patients
The genomic landscape of 2,023 colorectal cancers
Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome
Clonal KEAP1 mutations with loss of heterozygosity share reduced immunotherapy efficacy and low immune cell infiltration in lung adenocarcinoma
Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data
Algorithmic methods to infer the evolutionary trajectories in cancer progression
TRONCO: an R package for the inference of cancer progression models from heterogeneous genomic data
CAPRI: efficient inference of cancer progression models from cross-sectional data
Inferring Tree Causal Models of Cancer Progression with Probability Raising