Shinya Ito

Infant drug exposure via breast milk

Cognitive and behavioral risk factors for low quality of life in survivors of childhood acute lymphoblastic leukemia

Quantitative MRI outcomes in child and adolescent leukemia survivors: Evidence for global alterations in gray and white matter

Takeuchi M, Kobayashi T,  Biss  T,  Kamali  F,  Vear  SI, Ho RH,  Bajolle  F,  Loriot  M-A, Shaw K, Carleton BC,  Hamberg  A-K,  Wadelius  M,  Hirono  K, Taguchi M,  Wakamiya  T,  Yanagimachi  M, Hirai K, Itoh K,  Brandeo  LR,  Ito S . CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin

Reasons for substance use continuation and discontinuation during pregnancy: A qualitative study

Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations

Substance Use in Pregnancy Among Vulnerable Women Seeking Addiction and Parenting Support

Delaney S, Malik P, Stefan C, Edginton A, Colantonio D,  Ito S.  Predicting escitalopram exposure to breastfeeding infants: integrating analytical and in silico techniques for risk assessment.  Clin   Pharmacokinet  2018; 57 (12): 1603-1611

Evaluation of the Safety of Drugs and Biological Products Used During Lactation: Workshop Summary

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

Panchaud  A, Garcia-Bournissen F,  Csajka  C,  Kristensen  JH, Taddio A,  Ilet  KF,  Begg  EJ,  Ito S .  Prediction of infant drug exposure through breastfeeding: population PK modeling and simulation of fluoxetine.   Clin   Pharmacol   Ther   2011;89: 830–836 .    PMID: 21525869

Tan KP, Wang B, Yang M, Boutros PC, MacAulay J, Xu H, Chuang AI,  Kosuge  K, Yamamoto M, Takahashi S, Wu A, Ross DD, Harper PA,  Ito S .  Aryl hydrocarbon receptor (AHR) is a transcriptional activator of human breast cancer resistance protein (BCRP/ABCG2).  Mol   Pharmacol  2010;78:175-185      PMID

Ito S.  Drug therapy for breast-feeding women. New  Engl  J Med 2000; 343:118-126.   PMID: 10891521