Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Nutrition, Genetics, and Disease, and Diet and metabolism studies.
Asian diversity in human immune cells
Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases
Adiposity and metabolic health in Asian populations: an epidemiological study using dual-energy x-ray absorptiometry in Singapore
Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues
No evidence for a common blood microbiome based on a population study of 9,770 healthy humans
The Singapore National Precision Medicine Strategy
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases
Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts
Analysis of clinically relevant variants from ancestrally diverse Asian genomes
Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
The trans-ancestral genomic architecture of glycemic traits
DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases
Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype
Epigenetic Link Between Statin Therapy and Type 2 Diabetes
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults
Meta-Analysis of Maternal Prenatal Smoking GFI1-Locus and Cardio-Metabolic Phenotypes in Adults
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells
Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine–Induced Hand-Foot Syndrome
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
Erratum to: A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk