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Paul Aisen

University of Southern California · US
Area of research
Psychiatry and Mental health · Physiology
Research interest
Research interests include Dementia and Cognitive Impairment Research, Alzheimer's disease research and treatments, Health Systems, Economic Evaluations, Quality of Life, and Functional Brain Connectivity Studies.
h-index
85
citations
31,639
works
514
NIH funding
primary concept
email

Recent publications

Donanemab: Appropriate use recommendations
The Journal of Prevention of Alzheimer s Disease 2025cited by 137position: middledoi
Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study
Translational Psychiatry 2025cited by 3position: middledoi
Sleep chart of biological aging clocks in middle and late life
medRxiv 2025cited by 0position: middledoi
Overview of Alzheimer's Disease Neuroimaging Initiative and future clinical trials
Alzheimer s & Dementia 2024cited by 33position: middledoi
Differences in baseline cognitive performance between participants with early‐onset and late‐onset Alzheimer's disease: Comparison of LEADS and ADNI
Alzheimer s & Dementia 2024cited by 17position: middledoi
A Protocol for the Inclusion of Minoritized Persons in Alzheimer Disease Research From the ADNI3 Diversity Taskforce
JAMA Network Open 2024cited by 6position: middledoi
Plasma Aβ42/Aβ40 and phospho‐tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease
Alzheimer s & Dementia 2023cited by 137position: middledoi
Amyloid and tau‐PET in early‐onset AD: Baseline data from the Longitudinal Early‐onset Alzheimer's Disease Study (LEADS)
Alzheimer s & Dementia 2023cited by 79position: middledoi
Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease
JAMA Neurology 2023cited by 43position: middledoi
Natural cubic splines for the analysis of Alzheimer's clinical trials
Pharmaceutical Statistics 2023cited by 32position: middledoi
Sex and <i>APOE ε4</i> carrier effects on atrophy, amyloid PET, and tau PET burden in early‐onset Alzheimer's disease
Alzheimer s & Dementia 2023cited by 29position: middledoi
Profiling baseline performance on the Longitudinal Early‐Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection
Alzheimer s & Dementia 2023cited by 22position: middledoi
Cerebrospinal fluid biomarkers in the Longitudinal Early‐onset Alzheimer's Disease Study
Alzheimer s & Dementia 2023cited by 21position: middledoi
Designing the next-generation clinical care pathway for Alzheimer’s disease
Nature Aging 2022cited by 193position: middledoi
Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force
The Journal of Prevention of Alzheimer s Disease 2022cited by 120position: middledoi
Recommendations to address key recruitment challenges of Alzheimer's disease clinical trials
Alzheimer s & Dementia 2022cited by 104position: lastdoi
Meaningful benefits: a framework to assess disease-modifying therapies in preclinical and early Alzheimer’s disease
Alzheimer s Research & Therapy 2022cited by 71position: middledoi
Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI)
Alzheimer s & Dementia 2022cited by 43position: middledoi
Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease
Nature Communications 2022cited by 43position: middledoi
Improving generalizability and study design of Alzheimer's disease cohort studies in the United States by including under‐represented populations
Alzheimer s & Dementia 2022cited by 42position: middledoi
Tau positron emission tomography in preclinical Alzheimer’s disease
Brain 2022cited by 37position: middledoi
The Longitudinal Early‐onset Alzheimer's Disease Study (LEADS): Framework and methodology
Alzheimer s & Dementia 2021cited by 83position: middledoi
Detection of β-amyloid positivity in Alzheimer’s Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers
Brain Communications 2021cited by 81position: middledoi
State‐of‐the‐art of lumbar puncture and its place in the journey of patients with Alzheimer's disease
Alzheimer s & Dementia 2021cited by 75position: middledoi
Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study
Translational Psychiatry 2021cited by 69position: middledoi
Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management
Frontiers in Neurology 2021cited by 54position: middledoi
Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials
Journal of Neurology Neurosurgery & Psychiatry 2020cited by 480position: middledoi
Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia
JAMA Neurology 2020cited by 363position: lastdoi
Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals
JAMA Neurology 2020cited by 322position: middledoi
Neuroanatomical spread of amyloid β and tau in Alzheimer’s disease: implications for primary prevention
Brain Communications 2020cited by 113position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michael W. Weiner · Hôpital Beau-Séjour23 papers (2012–2024)Michael Donohue · University of Southern California18 papers (2014–2023)Ronald C. Petersen · University Hospital Leipzig16 papers (2012–2024)Rema Raman · ADS Group13 papers (2012–2023)Reisa A. Sperling · Harvard University12 papers (2013–2023)Clifford R. Jack · ADS Group10 papers (2012–2024)Andrew J. Saykin · Vanderbilt University Medical Center10 papers (2014–2024)Jeffrey L. Cummings · New York University8 papers (2012–2022)Laurel Beckett · Boston University7 papers (2014–2024)Leslie M. Shaw · Siemens (United States)7 papers (2012–2024)William J. Jagust · Berkeley College6 papers (2012–2024)Bruno Vellas · Hôpital de La Grave5 papers (2013–2022)Philip S. Insel · University of California, San Francisco5 papers (2015–2023)Keith A. Johnson · Howard University5 papers (2014–2023)John Q. Trojanowski · University of Pennsylvania5 papers (2012–2021)Michael S. Rafii · University of Southern California5 papers (2015–2025)Ronald G. Thomas · University of California San Diego Medical Center4 papers (2012–2014)Chung‐Kai Sun · National Yang Ming Chiao Tung University4 papers (2017–2020)Dorene M. Rentz · Brigham and Women's Hospital4 papers (2014–2015)Eric Siemers · Indiana University School of Medicine4 papers (2013–2020)