Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer Genomics and Diagnostics, Breast Cancer Treatment Studies, DNA Repair Mechanisms, and Gene expression and cancer classification.
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling
Translational and clinical comparison of whole genome and transcriptome to panel sequencing in precision oncology
COGNITION-GUIDE – Genomics-Guided Targeted Post-Neoadjuvant Therapy in Patients with Early Breast Cancer: Study Design of a Multicenter, Open-Label, Umbrella Phase II Study
Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling—The <scp>CATCH</scp> experience
Novel chimeric antigen receptors for the effective and safe treatment of NY‐BR‐1 positive breast cancer
Reimbursement in the Context of Precision Oncology Approaches in Metastatic Breast Cancer: Challenges and Experiences
131O A composite biomarker for evaluation of homologous recombination repair deficiency in a pan-cancer cohort
Association of mutation signature effectuating processes with mutation hotspots in driver genes and non-coding regions
COGNITION: a prospective precision oncology trial for patients with early breast cancer at high risk following neoadjuvant chemotherapy
Compositional complementarity between genomic RNA and coat proteins in positive-sense single-stranded RNA viruses
Tumor genetics and individualized therapy
CATCH: A Prospective Precision Oncology Trial in Metastatic Breast Cancer
The landscape of chromothripsis across adult cancer types
Unraveling most abundant mutational signatures in head and neck cancer
Chromothripsis in Human Breast Cancer
Dauerhaftes Ansprechen auf Olaparib und endokrine Therapie bei einer Patientin mit metastasiertem luminalem Mammakarzinom und gBRCA-Mutation
COGNITION - Präzisionsmedizin bei Brustkrebs im Frühstadium
Abstract 3496: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Improving personalised therapy in metastatic breast cancer by implementing RNA sequencing based gene expression signatures
Integrative genomic and transcriptomic analysis of leiomyosarcoma
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
A novel cloning strategy for one-step assembly of multiplex CRISPR vectors
Mismatch Repair Deficiency Drives Durable Complete Remission by Targeting Programmed Death Receptor 1 in a Metastatic Luminal Breast Cancer Patient
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Mutational signatures are correlated with common risk factors and survival of head and neck cancer patients
Mutationssignaturen korrelieren mit häufigen Risikofaktoren und mit dem Überleben von Kopf-Hals-Tumor-Patienten
Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer
Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis
Abstract 509: Genomic profiling of acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between <i>ATM</i> mutations and chromothripsis