Area of research
Physiology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Erythrocyte Function and Pathophysiology, Blood properties and coagulation, Hemoglobinopathies and Related Disorders, and RNA modifications and cancer.
HLTF cooperates with GATA1 to activate transcriptional programs and chromatin remodeling during erythroid development.
Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome.
RPS19 and RPL5 haploinsufficient models reveal divergent ribosomal subunit controls of fetal hematopoiesis.
Comprehensive phenotypic and proteomic analyses of human reticulocyte maturation
Regulation of Alternative Polyadenylation Events by PABPC1 Affects Erythroid Progenitor Cell Expansion
CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial.
RPS19 and RPL5 Haploinsufficient Models Reveal Divergent Ribosomal Subunit Controls of Fetal Hematopoiesis
Red cell shape regulation by band 3–ankyrin–spectrin linkage: implications for clinical severity of bovine hereditary spherocytosis
Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways.
Reply to Kaestner et al.: Pioneering quantitative platforms for stored red blood cell assessment open the door for precision transfusion medicine.
CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial
Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine
Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A.
Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine.
Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A
Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis
Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways
HEXIM1 is an essential transcription regulator during human erythropoiesis.
Kindlin-3 deficiency leads to impaired erythropoiesis and erythrocyte cytoskeleton.
Simultaneous adjunctive treatment of malaria and its coevolved genetic disorder sickle cell anemia.
New ASH initiatives to improve patient care in the long-overlooked sickle cell disease.
Parasite hijacks red cell membrane proteins.
HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation
HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation.
Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis.
Screen "play" for drug discovery.
Arginine-dependent hypusination of the eukaryotic translation initiation factor (eIF)5A drives erythroid lineage differentiation
p53 activation during ribosome biogenesis regulates normal erythroid differentiation
Impairment of human terminal erythroid differentiation by histone deacetylase 5 deficiency.
Comprehensive phenotyping of erythropoiesis in human bone marrow: Evaluation of normal and ineffective erythropoiesis