Area of research
Neurology · Cell Biology
Research interest
Research interests include LRRK2, Biology, Kinase, Neuroblastoma, Dimer, and Cancer research.
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43
Nanobodies as allosteric modulators of Parkinson’s disease–associated LRRK2
Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer
Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival
The LRRK2 Variant E193K Prevents Mitochondrial Fission Upon MPP+ Treatment by Altering LRRK2 Binding to DRP1
A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B‐cell lymphoma
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
Mutational dynamics between primary and relapse neuroblastomas
Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3