Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, Congenital heart defects research, Pluripotent Stem Cells Research, and Genomics and Rare Diseases.
Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes
The contribution of de novo coding mutations to meningomyelocele
The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the clinical validity of 111 gene-disease relationships
A single-cell time-lapse of mouse prenatal development from gastrula to birth
Improving laboratory animal genetic reporting: LAG-R guidelines
Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells
The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the Clinical Validity of 111 Gene-Disease Relationships
Focused ultrasound–mediated brain genome editing
Systematic reconstruction of cellular trajectories across mouse embryogenesis
Efficient in vivo neuronal genome editing in the mouse brain using nanocapsules containing CRISPR-Cas9 ribonucleoproteins
MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses
The NIH Somatic Cell Genome Editing program
Human and mouse essentiality screens as a resource for disease gene discovery
The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation
Prevalence of sexual dimorphism in mammalian phenotypic traits
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium
High-throughput discovery of novel developmental phenotypes
Genome wide conditional mouse knockout resources
MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates