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Nola M. Hylton

UCSF Helen Diller Family Comprehensive Cancer Center · US
🔎 Find collaborators in Radiology, Nuclear Medicine and Imaging · Cancer Research →
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Area of research
Radiology, Nuclear Medicine and Imaging · Cancer Research
Research interest
Research interests include MRI in cancer diagnosis, Breast Cancer Treatment Studies, Radiomics and Machine Learning in Medical Imaging, and Medical Imaging Techniques and Applications.
h-index
62
citations
14,456
works
374
NIH funding
primary concept
Medicine
email

Recent publications

Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ
JAMA Oncology 2025cited by 18position: middledoi
Combined prognostic impact of initial clinical stage and residual cancer burden after neoadjuvant systemic therapy in triple-negative and HER2-positive breast cancer: an analysis of the I-SPY2 randomized clinical trial
Breast Cancer Research 2025cited by 8position: middledoi
Immune Subtyping Identifies Patients With Hormone Receptor–Positive Early-Stage Breast Cancer Who Respond to Neoadjuvant Immunotherapy (IO): Results From Five IO Arms of the I-SPY2 Trial
JCO Precision Oncology 2025cited by 5position: middledoi
Ramalingam K, Woody R, Glencer A, Schwartz CJ, Mori H, Wong J, Hirst G, Rosenbluth J, Onishi N, Gibbs J, Hylton N, Borowsky AD, Campbell M, Esserman LJ. Intratumoral Injection of mRNA-2752 and Pembrolizumab for High-Risk Ductal Carcinoma In Situ: A Phase 1 Nonrandomized Clinical Trial. JAMA Oncol. 2
2025cited by 0position: selected
Li W, Onishi N, Gibbs JE, Wilmes LJ, Le NN, Metanat P, Price ER, Joe BN, Kornak J, Yau C, Wolf DM, Magbanua MJM, LeStage B, van 't Veer LJ, DeMichele AM, Esserman LJ, Hylton NM. MRI-Based Model for Personalizing Neoadjuvant Treatment in Breast Cancer. Tomography. 2025 Feb 27; 11(3).
2025cited by 0position: selected
Rugo HS, Campbell M, Yau C, Jo Chien A, Wallace AM, Isaacs C, Boughey JC, Han HS, Buxton M, Clennell JL, Asare SM, Steeg K, Wilson A, Singhrao R, Matthews JB, Perlmutter J, Fraser Symmans W, Hylton NM, DeMichele AM, Yee D, Van't Veer LJ, Berry DA, Esserman LJ. Pexidartinib and standard neoadjuvant t
2025cited by 0position: selected
Huppert LA, Wolf D, Yau C, Brown-Swigart L, Hirst GL, Isaacs C, Pusztai L, Pohlmann PR, DeMichele A, Shatsky R, Yee D, Thomas A, Nanda R, Perlmutter J, Heditsian D, Hylton N, Symmans F, Van't Veer LJ, Esserman L, Rugo HS. Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk
2025cited by 0position: selected
Datopotamab–deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial
Nature Medicine 2024cited by 38position: middledoi
Pathologic complete response (pCR) rates for patients with HR+/HER2− high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial
Annals of Oncology 2024cited by 22position: middledoi
Datopotamab–deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial
Nature Medicine 2024cited by 9position: middledoi
Li W, Le NN, Nadkarni R, Onishi N, Wilmes LJ, Gibbs JE, Price ER, Joe BN, Mukhtar RA, Gennatas ED, Kornak J, Magbanua MJM, Van't Veer LJ, LeStage B, Esserman LJ, Hylton NM. Tumor Morphology for Prediction of Poor Responses Early in Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter Retrospect
2024cited by 0position: selected
Greenwood HI, Maldonado Rodas CK, Freimanis RI, Glencer AC, Miller PN, Mukhtar RA, Brabham C, Yau C, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky A, Hylton N, Esserman LJ, Basu A. Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ. NPJ Breast Cancer
2024cited by 0position: selected
Magbanua MJM, Ahmed Z, Sayaman RW, Brown Swigart L, Hirst GL, Yau C, Wolf DM, Li W, Delson AL, Perlmutter J, Pohlmann P, Symmans WF, Yee D, Hylton NM, Esserman LJ, DeMichele AM, Rugo HS, van 't Veer LJ. Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Can
2024cited by 0position: selected
Diwanji D, Onishi N, Hathi DK, Lawhn-Heath C, Kornak J, Li W, Guo R, Molina-Vega J, Seo Y, Flavell RR, Heditsian D, Brain S, Esserman LJ, Joe BN, Hylton NM, Jones EF, Ray KM. 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy. Radiol Im
2024cited by 0position: selected
Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy
Cancer Cell 2023cited by 162position: middledoi
Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study
Radiology 2023cited by 82position: middledoi
Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial—Efficacy and Biomarker Discovery
Clinical Cancer Research 2023cited by 18position: middledoi
Abstract GS5-03: Evaluation of anti-PD-1 Cemiplimab plus anti-LAG-3 REGN3767 in early-stage, high-risk HER2-negative breast cancer: Results from the neoadjuvant I-SPY 2 TRIAL
Cancer Research 2023cited by 16position: middledoi
Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies
Cancer Cell 2022cited by 317position: middledoi
Deep Learning to Simulate Contrast-enhanced Breast MRI of Invasive Breast Cancer
Radiology 2022cited by 52position: middledoi
Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer
npj Breast Cancer 2022cited by 27position: middledoi
Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial
Cancer Cell 2021cited by 325position: middledoi
Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer
JAMA Oncology 2021cited by 106position: middledoi
Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial
Nature Communications 2021cited by 72position: middledoi
Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk
npj Breast Cancer 2021cited by 52position: middledoi
The Way of the Future: Personalizing Treatment Plans Through Technology
American Society of Clinical Oncology Educational Book 2021cited by 49position: middledoi
Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2−) breast cancer before chemo-endocrine therapy
Annals of Oncology 2021cited by 45position: middledoi
Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response
Radiology 2021cited by 36position: lastdoi
Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer
npj Breast Cancer 2021cited by 29position: middledoi
Response-guided treatment optimization in the I-SPY2 trial.
Journal of Clinical Oncology 2021cited by 7position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Laura J. Esserman · UCSF Helen Diller Family Comprehensive Cancer Center16 papers (2012–2025)David C. Newitt · University of California, San Francisco11 papers (2013–2021)Thomas L. Chenevert · University of Michigan–Ann Arbor9 papers (2014–2020)Savannah C. Partridge · University of Washington7 papers (2015–2020)Mitchell D. Schnall · ECOG-ACRIN Cancer Research Group6 papers (2012–2020)Mark Rosen · Amgen (United States)6 papers (2012–2018)Bonnie N. Joe · University of California, San Francisco6 papers (2013–2022)Dariya Malyarenko · University of Michigan5 papers (2014–2020)Gillian L. Hirst · UCSF Helen Diller Family Comprehensive Cancer Center5 papers (2017–2025)Helga S. Marques · Brown University5 papers (2012–2018)Angela DeMichele · Brigham and Women's Hospital5 papers (2015–2025)Jessica Gibbs · University of Georgia5 papers (2018–2025)Thomas E. Yankeelov · Livestrong Foundation5 papers (2014–2020)Lisa J. Wilmes · University of California, San Francisco5 papers (2015–2020)Douglas Yee · University of Minnesota5 papers (2015–2025)Jayashree Kalpathy–Cramer · Cicatelli Associates4 papers (2014–2017)Sandra M. Polin · Georgetown University4 papers (2012–2018)Christina Yau · Buck Institute for Research on Aging4 papers (2017–2025)Etta D. Pisano · Georgetown University4 papers (2012–2018)Wei Yang · Emory University4 papers (2017–2020)
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