Area of research
Molecular Biology · Immunology
Research interest
Research interests include Inflammasome and immune disorders, interferon and immune responses, Heme Oxygenase-1 and Carbon Monoxide, and Immune Response and Inflammation.
Gasdermins as evolutionarily conserved executors of inflammation and cell death
Apoptotic cell death in disease—Current understanding of the NCCD 2023
RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling
Antibody Afucosylation Augments CD16-Mediated Serial Killing and IFNγ Secretion by Human Natural Killer Cells
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
LPS targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation
IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection
Inflammasomes: mechanism of assembly, regulation and signalling
<scp>GSDMD</scp> membrane pore formation constitutes the mechanism of pyroptotic cell death
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida