Area of research
Public Health, Environmental and Occupational Health · Molecular Biology
Research interest
Research interests include Malaria Research and Control, HIV/AIDS drug development and treatment, RNA and protein synthesis mechanisms, and Biochemical and Molecular Research.
Systematic in vitro evolution in <i>Plasmodium falciparum</i> reveals key determinants of drug resistance
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple <i>Plasmodium</i> kinases and life cycle stages
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Using <i>in Vitro</i> Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
Target Validation and Identification of Novel Boronate Inhibitors of the <i>Plasmodium falciparum</i> Proteasome