Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Ferroptosis and cancer prognosis, Epigenetics and DNA Methylation, and Metabolism, Diabetes, and Cancer.
Correction: Metabolic state uncovers prognosis insights of esophageal squamous cell carcinoma patients.
Multi-Modal Metabolomics Deciphers Pan-Cancer Metabolic Landscapes and Spatial-Niche-Specific Alternations.
Dissecting origin factors of lymph node metastasis in non-small cell lung cancer via multimodal omics.
Branched-chain α-keto acids impair glucose-stimulated insulin secretion in pancreatic β-cells under diabetes by reactivating the LDHA-lactate axis.
Peritumoural adipose tissue promotes ferroptosis resistance by 3-hydroxykynurenine-mediated suppression of ferritinophagy.
Overcoming missing data in spatial metabolomics with machine learning imputation to accelerate downstream discovery
SUMC reveals conserved and context-specific tumor microenvironment architectures across heterogeneous spatial datasets
S-palmitoylation of MTDH regulates ferroptosis resistance in breast cancer cell
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing.
Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Metabolic state uncovers prognosis insights of esophageal squamous cell carcinoma patients.
Author Correction: Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Exploring the metabolic signaling network of GFPT in cancer.
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma.
A preserved TGFβ cytostatic response through DLD-mediated metabolic modulation undermines anti-TGFβ therapy in gastric cancer.
The pyruvate dehydrogenase complex in concert with the DNA/RNA-binding protein YBX1 regulates cell senescence and tumorigenesis
Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis
Correction: KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC.
Uncovering Anticancer Mechanisms of Spiramycin Derivatives Using Transcriptomic and Metabolomic Analyses.
Enhancer regulator MLL4 controls skeletal muscle metabolic efficiency by limiting AMPK-mediated fuel catabolism.
MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice
MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice.
Malate initiates a proton-sensing pathway essential for pH regulation of inflammation
Integrated proteogenomic and metabolomic characterization of papillary thyroid cancer with different recurrence risks.
AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine.
Malate initiates a proton-sensing pathway essential for pH regulation of inflammation.
KEAP1 promotes anti-tumor immunity by inhibiting PD-L1 expression in NSCLC.
Exploring Protein <i>S</i>-Palmitoylation: Mechanisms, Detection, and Strategies for Inhibitor Discovery.
AMPK-PDZD8-GLS1 axis mediates calorie restriction-induced lifespan extension.
Diagnosis and prognosis prediction of gastric cancer by high-performance serum lipidome fingerprints.