Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include RNA modifications and cancer, Cancer-related molecular mechanisms research, MicroRNA in disease regulation, and RNA Research and Splicing.
CLDN18.2–targeting antibody–drug conjugate IBI343 in advanced gastric or gastroesophageal junction adenocarcinoma: a phase 1 trial
CREB1 contributes colorectal cancer cell plasticity by regulating lncRNA CCAT1 and NF-κB pathways
Detection of ovarian cancer using plasma cell-free DNA methylomes
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development
Ribosome profiling analysis identified a KRAS-interacting microprotein that represses oncogenic signaling in hepatocellular carcinoma cells
Comprehensive Genomic Characterization of RNA-Binding Proteins across Human Cancers
Inhibition of the JNK/MAPK signaling pathway by myogenesis-associated miRNAs is required for skeletal muscle development
miR‐372 and miR‐373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways
Oridonin induces autophagy via inhibition of glucose metabolism in p53-mutated colorectal cancer cells
ChIPBase v2.0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data
deepBase v2.0: identification, expression, evolution and function of small RNAs, LncRNAs and circular RNAs from deep-sequencing data
RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data
Discovery of Protein–lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets
Inhibition of miR-17 and miR-20a by Oridonin Triggers Apoptosis and Reverses Chemoresistance by Derepressing BIM-S
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data
ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data
RTL-P: a sensitive approach for detecting sites of 2′-O-methylation in RNA molecules
Triggering Fbw7-Mediated Proteasomal Degradation of c-Myc by Oridonin Induces Cell Growth Inhibition and Apoptosis
MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion