Area of research
Cell Biology · Biomedical Engineering
Research interest
Research interests include Cellular Mechanics and Interactions, 3D Printing in Biomedical Research, Cancer Cells and Metastasis, and Cell Adhesion Molecules Research.
Mechanometabolism: recent findings on the intersection of cell adhesion, cell migration, and metabolism
Tension directs cancer cell migration over fiber alignment through energy minimization
Mitochondrial transfer from cancer-associated fibroblasts increases migration in aggressive breast cancer
Matrix stiffness enhances cancer-macrophage interactions and M2-like macrophage accumulation in the breast tumor microenvironment
Highly motile cells are metabolically responsive to collagen density
Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening
Mechanoresponsive metabolism in cancer cell migration and metastasis
Cancer cell metabolic plasticity in migration and metastasis
Phenotypic Heterogeneity and Metastasis of Breast Cancer Cells
Matrix-driven changes in metabolism support cytoskeletal activity to promote cell migration
Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression
Energetic regulation of coordinated leader–follower dynamics during collective invasion of breast cancer cells
Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making
Fiber alignment drives changes in architectural and mechanical features in collagen matrices
Engineered models to parse apart the metastatic cascade
Matrix stiffness regulates microvesicle-induced fibroblast activation
Targeting extracellular matrix stiffness to attenuate disease: From molecular mechanisms to clinical trials
Mechanical Forces in Tumor Angiogenesis
Matrix stiffness regulates vascular integrity through focal adhesion kinase activity
Regulation of ATP utilization during metastatic cell migration by collagen architecture
Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype
Matrix stiffness enhances VEGFR-2 internalization, signaling, and proliferation in endothelial cells
Matrix stiffening promotes a tumor vasculature phenotype
3D Bioprinting of Spatially Heterogeneous Collagen Constructs for Cartilage Tissue Engineering
Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation
The Mechanics of Single Cell and Collective Migration of Tumor Cells
Local extracellular matrix alignment directs cellular protrusion dynamics and migration through Rac1 and FAK
Improving fascin inhibitors to block tumor cell migration and metastasis
Age-related vascular stiffening: causes and consequences
Cooperative Effects of Matrix Stiffness and Fluid Shear Stress on Endothelial Cell Behavior