Area of research
Oncology · Molecular Biology
Research interest
Research interests include Colorectal Cancer Treatments and Studies, Biochemical and Molecular Research, Pancreatic and Hepatic Oncology Research, and Lung Cancer Treatments and Mutations.
The Role of the Ecto-Nucleotidases CD73 and CD39 in Chemo- and Immunotherapy.
Academia Europaea’s guidelines for the visualization of clinical outcomes
Obatoclax enhances TRAIL-induced apoptosis in non-small-cell-lung-cancer cells by increasing TRAIL receptor expression, priming for mitochondrial apoptosis and reducing XIAP levels
Differential molecular mechanisms of bortezomib sensitization to rhTRAIL in non-small cell lung cancer cell lines.
Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target.
Looking for the unexpected in purine and pyrimidine metabolism.
G-Protein Signaling Modulator 2 as a Potential Biomarker in Colorectal Cancer: Integrative Analysis Using Genetic Profiling and Pan-Cancer Studies.
The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity.
Mechanisms underlying reversed TRAIL sensitivity in acquired bortezomib-resistant non-small cell lung cancer cells.
Management of neurological symptoms in Lesch-Nyhan disease: A systematic review.
Nucleo(s)tide metabolism as basis for drug development; the Anne Simmonds award lecture.
Corrigendum to "Discovery of anticancer agents with c-Met inhibitory potential by virtual and experimental screening of a chemical library" [Europ. J. Pharmacol. (2023) 938: 175395].
Newly synthesized acridone derivatives targeting lung cancer: A toxicity and xenograft model study.
Pegylated nanoliposomal cisplatin ameliorates chemotherapy-induced peripheral neuropathy.
Evaluation of N4-hydroxycytidine incorporation into nucleic acids of SARS-CoV-2-infected host cells by direct measurement with liquid chromatography-mass spectrometry.
Effects of lactate dehydrogenase A and GLUT1 inhibition on human endothelial cell migration in relation to their intracellular nucleotide pool.
Pharmacological mechanisms underlying the interaction of the nucleoside analogue gemcitabine with the c-MET inhibitor tivantinib in pancreatic cancer.
Exploring the role of oxidative stress and the effect of N-acetylcysteine in thiopurine-induced liver injury in inflammatory bowel disease: A randomized crossover pilot study.
Effects of nucleoside analogues, lipophilic prodrugs and elaidic acids on core signaling pathways in cancer cells.
Novel mass spectrometry-based assay for thymidylate synthase activity.
Evaluation of the combination of gemcitabine, carboplatin, and lactate dehydrogenase A inhibitor on malignant mesothelioma.
Obituary to Lynette Fairbanks, PhD
Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing.
Role of exosomes in transferring chemoresistance through modulation of cancer glycolytic cell metabolism.
Targeting miRNA and using miRNA as potential therapeutic options to bypass resistance in pancreatic ductal adenocarcinoma.
Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma.
Target Therapy in Malignant Pleural Mesothelioma: Hope or Mirage?
The Prognostic Value of <i>ASPHD1</i> and <i>ZBTB12</i> in Colorectal Cancer: A Machine Learning-Based Integrated Bioinformatics Approach.
Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo.
Extracellular vesicles: Emerging mediators of cell communication in gastrointestinal cancers exhibiting metabolic abnormalities.