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Takao Deguchi

National Center For Child Health and Development · JP
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Area of research
Public Health, Environmental and Occupational Health · Hematology
Research interest
Research interests include Acute Lymphoblastic Leukemia research, Acute Myeloid Leukemia Research, Childhood Cancer Survivors' Quality of Life, and Chronic Myeloid Leukemia Treatments.
h-index
35
citations
3,835
works
256
NIH funding
primary concept
Medicine
email

Recent publications

Clinical and molecular characterization of thrombocytosis in transient abnormal myelopoiesis.
2026cited by 0position: contributordoi
JCCG ALL-B12: Evaluation of Intensified Therapies With Vincristine/Dexamethasone Pulses and Asparaginase and Augmented High-Dose Methotrexate for Pediatric B-ALL.
2025cited by 9position: contributordoi
A prospective study evaluating the safety and pharmacokinetics of ponatinib at a fixed dose in six paediatric patients with philadelphia chromosome‐positive leukaemia: <scp>JCCG PedPona19</scp> study
British Journal of Haematology 2025cited by 1position: contributordoi
Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms
Blood 2024cited by 22position: middledoi
Landscape of driver mutations and their clinical effects on Down syndrome-related myeloid neoplasms.
2024cited by 17position: contributordoi
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies <i>LMO2/STAG2</i> Rearrangements as Extremely High Risk
Cancer Discovery 2024cited by 13position: middledoi
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk.
2024cited by 13position: contributordoi
High-dose cytarabine induction therapy and flow cytometric measurable residual disease monitoring for children with acute myeloid leukemia.
2024cited by 6position: contributordoi
TBI, etoposide, and cyclophosphamide conditioning for intermediate-risk relapsed childhood acute lymphoblastic leukemia.
2024cited by 1position: contributordoi
HLA-haploidentical T-cell receptor αβT/B-cell-depleted stem cell transplantation for Fanconi anemia.
2024cited by 0position: contributordoi
Hematopoietic stem cell transplantation in two sisters with bone marrow failure associated with POLE gene variants
2024cited by 0position: contributordoi
Successful management with urgent haploidentical-peripheral blood stem cell transplantation for a patient with severe aplastic anaemia who developed disseminated fungal infection following immunosuppressive therapy.
2024cited by 0position: contributordoi
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
2023cited by 22position: contributordoi
Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group.
2023cited by 15position: contributordoi
Safety and efficacy of post-haematopoietic cell transplantation maintenance therapy with blinatumomab for relapsed/refractory CD19-positive B-cell acute lymphoblastic leukaemia: protocol for a phase I-II, multicentre, non-blinded, non-controlled trial (JPLSG SCT-ALL-BLIN21).
2023cited by 5position: contributordoi
Impact of asparaginase discontinuation on outcomes of children with acute lymphoblastic leukaemia receiving the Japan Association of Childhood Leukaemia Study ALL-02 protocol.
2023cited by 5position: contributordoi
Acute monocytic leukemia with KMT2A::LASP1 developed 9 months after diagnosis of acute megakaryoblastic leukemia in a 2-year-old boy.
2023cited by 1position: contributordoi
Outcome of hematopoietic stem cell transplantation in pediatric patients with acute lymphoblastic leukemia not in remission enrolled in JACLS ALL-02.
2023cited by 1position: contributordoi
Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.
2022cited by 28position: contributordoi
A phase III clinical trial evaluating efficacy and safety of minimal residual disease-based risk stratification for children with acute myeloid leukemia, incorporating a randomized study of gemtuzumab ozogamicin in combination with post-induction chemotherapy for non-low-risk patients (JPLSG-AML-20).
2022cited by 11position: contributordoi
JACLS ALL-02 SR protocol reduced-intensity chemotherapy produces excellent outcomes in patients with low-risk childhood acute lymphoblastic leukemia.
2022cited by 5position: contributordoi
A pilot study of game-based learning programs for childhood cancer survivors.
2022cited by 4position: contributordoi
Successful hematopoietic stem cell transplantation with reduced dose of busulfan for Omenn syndrome.
2022cited by 0position: contributordoi
Labile CD22 and CD19 expression in a case of Philadelphia chromosome-like acute lymphoblastic leukemia.
2022cited by 0position: contributordoi
Predictive factors for the development of leukemia in patients with transient abnormal myelopoiesis and Down syndrome.
2021cited by 21position: contributordoi
Hematopoietic stem cell transplantation for infants with high-risk KMT2A gene-rearranged acute lymphoblastic leukemia.
2021cited by 16position: contributordoi
Successful Umbilical Cord Blood Transplantation With Reduced-intensity Conditioning for Acute Myeloid Leukemia in a Child With Shwachman-Diamond Syndrome.
2021cited by 1position: contributordoi
A case of KMT2A-MLLT3 fusion-positive mature B-cell acute lymphoblastic leukemia.
2021cited by 1position: contributordoi
Prednisolone poor response is not an indication for HSCT in pediatric B-cell precursor acute lymphoblastic leukemia in first remission: results from JACLS ALL-02 study.
2021cited by 1position: contributordoi
Correction to: FLEND (nelarabine, fludarabine, and etoposide) for relapsed T-cell acute lymphoblastic leukemia in children: a report from Japan Children's Cancer Group.
2021cited by 0position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

Toshihiko Imamura · Kyoto Prefectural University of Medicine9 papers (2019–2023)Motohiro Kato · Children's Cancer Center8 papers (2019–2025) · 8 papers (2020–2026) · 7 papers (2020–2024)Daisuke Tomizawa · National Center For Child Health and Development7 papers (2020–2024)Akiko Saito · Nagoya University Hospital5 papers (2021–2025) · 5 papers (2020–2023) · 5 papers (2021–2025)Masashi Sanada · National Hospital Organization4 papers (2020–2025) · 4 papers (2020–2024) · 4 papers (2020–2023) · 4 papers (2020–2025)Keizo Horibe · National Hospital Organization4 papers (2020–2025)Atsushi Manabe · Health Sciences University of Hokkaido3 papers (2020–2025)Katsuyoshi Koh · Saitama Children's Medical Center3 papers (2021–2025)Tomoo Osumi · National Center For Child Health and Development3 papers (2020–2021)Nobutaka Kiyokawa · National Center For Child Health and Development3 papers (2024–2025)Etsuro Ito · Hirosaki University3 papers (2021–2026) · 3 papers (2021–2025)Kimiyoshi Sakaguchi · Hamamatsu Ika Daigaku3 papers (2020–2023)
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