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James C. Costello

University of Colorado Cancer Center · US
Area of research
Pulmonary and Respiratory Medicine · Surgery
Research interest
Research interests include Bladder and Urothelial Cancer Treatments, Epigenetics and DNA Methylation, Ferroptosis and cancer prognosis, and Prostate Cancer Treatment and Research.
h-index
44
citations
12,059
works
348
NIH funding
primary concept
email

Recent publications

Respiratory viral infections awaken metastatic breast cancer cells in lungs
Nature 2025cited by 51position: middledoi
Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research
Cell Reports Medicine 2023cited by 37position: middledoi
Microparticle-Delivered Cxcl9 Prolongs Braf Inhibitor Efficacy in Melanoma
Cancer Immunology Research 2023cited by 4position: middledoi
A Crowdsourcing Approach to Develop Machine Learning Models to Quantify Radiographic Joint Damage in Rheumatoid Arthritis
JAMA Network Open 2022cited by 24position: middledoi
Microparticle-delivered Cxcl9 prolongs Braf inhibitor efficacy in melanoma
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 0position: middledoi
Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth
Cell Reports Medicine 2021cited by 106position: lastdoi
Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia
Cancer Discovery 2020cited by 542position: middledoi
ImmGen at 15
Nature Immunology 2020cited by 79position: middledoi
Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers
Molecular Cancer Research 2020cited by 34position: middledoi
Next-Generation Machine Learning for Biological Networks
Cell 2018cited by 969position: middledoi
Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes
Cell Reports 2017cited by 83position: middledoi
Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data
The Lancet Oncology 2016cited by 143position: middledoi
<i>TERT</i> promoter mutations and telomerase reactivation in urothelial cancer
Science 2015cited by 295position: middledoi
Coordinate Loss of <i>MAP3K7</i> and <i>CHD1</i> Promotes Aggressive Prostate Cancer
Cancer Research 2015cited by 87position: middledoi
A community effort to assess and improve drug sensitivity prediction algorithms
Nature Biotechnology 2014cited by 824position: middledoi
A community computational challenge to predict the activity of pairs of compounds
Nature Biotechnology 2014cited by 338position: middledoi
Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells
Science Translational Medicine 2013cited by 554position: middledoi
Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells
Stem Cell Reports 2013cited by 104position: middledoi
Differential splicing across immune system lineages
Proceedings of the National Academy of Sciences 2013cited by 93position: middledoi
Seeking the Wisdom of Crowds Through Challenge-Based Competitions in Biomedical Research
Clinical Pharmacology & Therapeutics 2013cited by 51position: firstdoi
Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate‐sparing anabolic therapy
Aging Cell 2013cited by 18position: middledoi
Wisdom of crowds for robust gene network inference
Nature Methods 2012cited by 1,770position: middledoi
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma
Nature Medicine 2012cited by 364position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Gustavo Stolovitzky · New York University5 papers (2012–2021)Jennifer A. Wargo · The University of Texas MD Anderson Cancer Center3 papers (2012–2023)Lawrence N. Kwong · The University of Texas MD Anderson Cancer Center3 papers (2012–2023)James J. Collins · Broad Institute of MIT and Harvard3 papers (2012–2018) · 3 papers (2012–2023)Thomas R. Cech · Howard Hughes Medical Institute3 papers (2015–2020)Alexander J. Lazar · Disco (Germany)2 papers (2022–2023)Michael P. Menden · Biotechnology Institute2 papers (2014–2014)Mukesh Bansal · Columbia University2 papers (2014–2014)Dinah S. Singer · Center for Cancer Research2 papers (2014–2014)Lindsay N. Barger · Drexel University2 papers (2022–2023)Franklin W. Huang · UCSF Helen Diller Family Comprehensive Cancer Center2 papers (2017–2020)Laura M. Heiser · Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie2 papers (2014–2014) · 2 papers (2022–2023) · 2 papers (2022–2023)Diogo M. Camacho · Harvard University2 papers (2012–2018)Julio Sáez-Rodríguez · European Bioinformatics Institute2 papers (2014–2014)Olivia El Naggar · Drexel University2 papers (2022–2023)Francesca Paradiso · Addgene2 papers (2022–2023)Gabriele Romano · Drexel University2 papers (2022–2023)