← back to search

Alexander Brobeil

University Hospital Heidelberg · DE
Area of research
Molecular Biology · Artificial Intelligence
Research interest
Research interests include Biology, Colorectal cancer, Medicine, Cancer research, Artificial intelligence, and Cancer.
h-index
citations
964
works
39
NIH funding
primary concept
email

Recent publications

Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma
Science Immunology 2025cited by 19position: middledoi
Rethinking cancer of unknown primary: from diagnostic challenge to targeted treatment
Nature Reviews Clinical Oncology 2025cited by 5position: middledoi
A Unique Signature for Cancer‐Associated Fibroblasts in Melanoma Metastases
Pigment Cell & Melanoma Research 2025cited by 5position: middledoi
Methylation-based smoking signatures in blood and tissue samples for the prediction of self-reported smoking status and mortality in patients with colorectal cancer
Clinical Epigenetics 2025cited by 2position: middledoi
DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms
Nature Communications 2025cited by 2position: middledoi
Expression of Bovine Meat and Milk Factor in Hepatocellular Carcinoma and Colorectal Liver Metastasis Patients
Journal of Medical Virology 2025cited by 1position: middledoi
Validation of novel low-dose CT methods for quantifying bone marrow in the appendicular skeleton of patients with multiple myeloma: initial results from the [18F]FDG PET/CT sub-study of the Phase 3 GMMG-HD7 Trial
European Journal of Nuclear Medicine and Molecular Imaging 2025cited by 1position: middledoi
Identification and external validation of tumor DNA methylation panel for the recurrence risk stratification of stage II colon cancer
Translational Oncology 2025cited by 1position: middledoi
Regression-based Deep-Learning predicts molecular biomarkers from pathology slides
Nature Communications 2024cited by 94position: middledoi
Multimodal and spatially resolved profiling identifies distinct patterns of T cell infiltration in nodal B cell lymphoma entities
Nature Cell Biology 2024cited by 62position: middledoi
Deep learning for dual detection of microsatellite instability and POLE mutations in colorectal cancer histopathology
npj Precision Oncology 2024cited by 26position: middledoi
Automated curation of large‐scale cancer histopathology image datasets using deep learning
Histopathology 2024cited by 7position: middledoi
PITX2 as a Sensitive and Specific Marker of Midgut Neuroendocrine Tumors: Results from a Cohort of 1157 Primary Neuroendocrine Neoplasms
Modern Pathology 2024cited by 7position: middledoi
N‐cadherin: A diagnostic marker to help discriminate primary liver carcinomas from extrahepatic carcinomas
International Journal of Cancer 2024cited by 7position: middledoi
Large-scale external validation and meta-analysis of gene methylation biomarkers in tumor tissue for colorectal cancer prognosis
EBioMedicine 2024cited by 5position: middledoi
Differential Immunoexpression of Inhibitory Immune Checkpoint Molecules and Clinicopathological Correlates in Keratoacanthoma, Primary Cutaneous Squamous Cell Carcinoma and Metastases
Acta Dermato Venereologica 2024cited by 2position: middledoi
Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study
Cell Reports Medicine 2023cited by 95position: middledoi
End-to-end prognostication in colorectal cancer by deep learning: a retrospective, multicentre study
The Lancet Digital Health 2023cited by 84position: middledoi
Encrypted federated learning for secure decentralized collaboration in cancer image analysis
Medical Image Analysis 2023cited by 80position: middledoi
Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma
Nature Communications 2023cited by 50position: middledoi
Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level
Nature Communications 2023cited by 35position: middledoi
Deep Learning–Enabled Diagnosis of Liver Adenocarcinoma
Gastroenterology 2023cited by 26position: middledoi
Bovine meat and milk factor protein expression in tumor‐free mucosa of colorectal cancer patients coincides with macrophages and might interfere with patient survival
Molecular Oncology 2023cited by 9position: middledoi
Spatial Dissection of the Bone Marrow Microenvironment in Multiple Myeloma By High Dimensional Multiplex Tissue Imaging
Blood 2023cited by 4position: middledoi
High-throughput electron tomography identifies centriole over-elongation as an early event in plasma cell disorders
Leukemia 2023cited by 2position: middledoi
CpG-biomarkers in tumor tissue and prediction models for the survival of colorectal cancer: A systematic review and external validation study
Critical Reviews in Oncology/Hematology 2023cited by 2position: middledoi
Validation of the prognostic value of <scp>CD3</scp> and <scp>CD8</scp> cell densities analogous to the Immunoscore® by stage and location of colorectal cancer: an independent patient cohort study
The Journal of Pathology Clinical Research 2022cited by 16position: middledoi
IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells
Journal for ImmunoTherapy of Cancer 2022cited by 11position: middledoi
Multimodal and spatially resolved profiling identifies distinct patterns of T-cell infiltration in nodal B-cell lymphoma entities
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 11position: middledoi
Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis
British Journal of Cancer 2022cited by 8position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michael Hoffmeister · Festo (Germany)13 papers (2021–2025)Hermann Brenner · Stanford University13 papers (2021–2025)Jakob Nikolas Kather · Ludwig-Maximilians-Universität München9 papers (2021–2024)Tanwei Yuan · German Cancer Research Center8 papers (2023–2025)Carsten Müller‐Tidow · Heidelberg University8 papers (2021–2024)Niels Weinhold · Sylvester Comprehensive Cancer Center7 papers (2021–2025)Hartmut Goldschmidt · Virginia Cooperative Extension7 papers (2021–2025)Marc S. Raab · Memorial Sloan Kettering Cancer Center7 papers (2021–2025)Titus J. Brinker · National Center for Tumor Diseases6 papers (2021–2024)Wilfried Roth · Johannes Gutenberg University Mainz6 papers (2022–2025)Nicholas P. West · University of Leeds5 papers (2021–2024)Philip Quirke · University of Leeds5 papers (2021–2024)Katrin E. Tagscherer · Johannes Gutenberg University Mainz5 papers (2022–2025)Melanie Bewerunge‐Hudler · German Cancer Research Center4 papers (2023–2025)Claudia Ernst · German Cancer Research Center4 papers (2021–2025)Matthias Kloor · European Molecular Biology Organization4 papers (2021–2025)Lukas John · University of Hohenheim4 papers (2021–2025)Elizabeth Alwers · Heidelberg University4 papers (2021–2023)Dominic Edelmann · German Cancer Research Center4 papers (2023–2025)Heike I. Grabsch · Maastricht University4 papers (2021–2024)