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J. Brent Richards

University of London ·
Area of research
Genetics · Orthopedics and Sports Medicine
Research interest
Research interests include Genetic Associations and Epidemiology, Bone health and osteoporosis research, Vitamin D Research Studies, and COVID-19 Clinical Research Studies.
h-index
86
citations
39,288
works
375
NIH funding
primary concept
Medicine
email

Recent publications

Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease
Nature Genetics 2025cited by 25position: lastdoi
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
Nature Communications 2024cited by 72position: middledoi
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers
Nature Communications 2024cited by 28position: middledoi
Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity
Nature Communications 2024cited by 19position: middledoi
A plasma protein-based risk score to predict hip fractures
Nature Aging 2024cited by 12position: middledoi
Systematic assessment of COVID-19 host genetics using whole genome sequencing data
PLoS Pathogens 2024cited by 1position: middledoi
Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases
Nature Genetics 2023cited by 954position: lastdoi
Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity
Nature Metabolism 2023cited by 111position: lastdoi
Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration
Cell Reports Medicine 2023cited by 40position: middledoi
Alternative splicing in lung influences COVID-19 severity and respiratory diseases
Nature Communications 2023cited by 34position: lastdoi
Dose-dependent Association of Alcohol Consumption With Obesity and Type 2 Diabetes: Mendelian Randomization Analyses
The Journal of Clinical Endocrinology & Metabolism 2023cited by 30position: lastdoi
HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases
Communications Biology 2023cited by 28position: lastdoi
Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis
Nature Genetics 2023cited by 27position: middledoi
Proteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection
Communications Medicine 2023cited by 20position: middledoi
Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19
Nature Genetics 2022cited by 126position: middledoi
Cohort profile: genomic data for 26 622 individuals from the Canadian Longitudinal Study on Aging (CLSA)
BMJ Open 2022cited by 80position: middledoi
An effector index to predict target genes at GWAS loci
Human Genetics 2022cited by 74position: lastdoi
Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study
Biological Psychiatry 2022cited by 53position: lastdoi
Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of <i>MUC5B</i> and <i>DSP</i> in Idiopathic Pulmonary Fibrosis
American Journal of Respiratory and Critical Care Medicine 2022cited by 41position: middledoi
ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19
Nature Communications 2022cited by 33position: middledoi
Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases
Genetics in Medicine 2022cited by 32position: middledoi
Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements
Cancer Epidemiology Biomarkers & Prevention 2022cited by 14position: lastdoi
Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization
JAMA 2021cited by 3,912position: lastdoi
Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration
BMJ 2021cited by 1,660position: lastdoi
Mapping the human genetic architecture of COVID-19
Nature 2021cited by 1,112position: middledoi
The health effects of vitamin D supplementation: evidence from human studies
Nature Reviews Endocrinology 2021cited by 490position: lastdoi
Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps
Nature Medicine 2021cited by 435position: middledoi
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity
Nature Medicine 2021cited by 297position: lastdoi
<i>Dnmt3a</i> -mutated clonal hematopoiesis promotes osteoporosis
The Journal of Experimental Medicine 2021cited by 155position: middledoi
Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study
PLoS Medicine 2021cited by 122position: lastdoi

Grants

CAREER: Design Rules for Electrical Transport in Suspensions of Conductive Particles
NSF2047365$692,1762021–2026PIRePORTER
Collaborative Research: The Impact of Climate Change on the Physics and Biology of the Ocean on Scales Down to the Submesoscale
NSF1658550$786,2922017–2021PIRePORTER
Collaborative Research: Mixing in the Equatorial Thermocline (MIXET)
NSF1029722$997,1852010–2016PIRePORTER
Scale interactions in the equatorial ocean
NSF0751962$528,2682008–2013PIRePORTER
SGER: Measurements of the Velocity Field Associated with Interleaving
NSF0741426$117,3302007–2009PIRePORTER
Mixing in the equatorial Pacific: the role of interleaving
NSF0326630$346,3152003–2007PIRePORTER
District 11 Earth and Weather Studies Program (DEWS)
NSF0122174$30,2752002–2003PIRePORTER
District Eleven Weather Study Program
NSF9613103$43,5531997–2001PIRePORTER
District Eleven Weather Study Program (DEWS)
NSF9222395$20,3251992–1996PIRePORTER
District Eleven Weather Study Program (DEWS) of Community School District 11
NSF9016561$6,0451990–1992PIRePORTER
The Debate Over Evolutionary Theory in Germany
NSF8821604$39,0001989–1992PIRePORTER
"Doctoral Dissentation Research in History and Philosophy ofScience"
NSF8910472$3,8001989–1990PIRePORTER
Community School District II - Summary of the District Eleven Weather Study Program (DEWS)
NSF8822383$6,3701988–1990PIRePORTER
The Emergence of Evolutionary Theories of Mind and Behavior
NSF8025064$5,0001981–1983PIRePORTER

Frequent collaborators

Vincenzo Forgetta · Jewish General Hospital24 papers (2014–2023)Celia M.T. Greenwood · McGill University14 papers (2012–2023)George Davey Smith · Laboratoire d’immunologie intégrative du cancer13 papers (2015–2021)Claudia Langenberg · Translational Therapeutics (United States)10 papers (2014–2023)Despoina Manousaki · University of Bergen9 papers (2016–2021)Sirui Zhou · McGill University Health Centre9 papers (2016–2023)Tim D. Spector · US Forest Service9 papers (2012–2017)Tomoko Nakanishi · Japan Society for the Promotion of Science8 papers (2020–2023)Hou‐Feng Zheng · Fudan University8 papers (2012–2019)Guillaume Butler‐Laporte · McGill University8 papers (2020–2023)Zari Dastani · McGill University Health Centre8 papers (2012–2014)John Morris · University of Toronto8 papers (2016–2022)Tianyuan Lu · Xuzhou Medical College7 papers (2020–2023)Lauren E. Mokry · Jewish General Hospital7 papers (2014–2020)Ruth E. Mitchell · University of Bristol5 papers (2019–2021)Niki Dimou · Centre international de recherche sur le cancer4 papers (2019–2021)Veronika Skrivankova · University of Bern4 papers (2019–2021)Rebecca C. Richmond · University of Bristol4 papers (2019–2021)Matthias Egger · Ludwig-Maximilians-Universität München4 papers (2019–2021)Scott G. Wilson · The University of Western Australia4 papers (2012–2017)