Area of research
Molecular Biology · Developmental Neuroscience · malaraia drug · malaraia drug desi
Research interest
Our laboratory pursues diverse research endeavors—from neural regeneration to disease modeling and drug discovery—while fostering close collaborations with Keio University and RIKEN to advance seamless, integrated research from bench to bedside.
Diagnostic potential of cryptic exon-derived peptides in serum extracellular vesicles for sporadic amyotrophic lateral sclerosis.
Human induced pluripotent stem cell-derived neural stem/progenitor cell therapy for spinal cord injury: preclinical advances and translational perspectives.
PDGFRα-positive mesenchymal stem/stromal cells contribute to autonomous vascular formation through in-body tissue architecture.
Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster
Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster
Author response: Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster
Ropinirole hydrochloride mitigates oxidative stress and neuroinflammation via the PI3K–mTOR pathway in TDP-43 hiPSC-derived microglial-like cells
Therapeutic frontiers in ALS: iPSC-based drug discovery, cell therapy, and gene therapy—Advances through 2026
A framework for neural organoids, assembloids and transplantation studies.
Phase separated condensates of ATRX regulate neural progenitor identity.
NEUROD1 efficiently converts peripheral blood cells into neurons with partial reprogramming by pluripotency factors.
Multi-organ frailty is enhanced by periodontitis-induced inflammaging.
Chiral shift toward D-serine reflects intrathecal inflammation in multiple sclerosis and counteracts motor impairment in a murine model
Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons.
Impaired synaptosome phagocytosis in macrophages of individuals with autism spectrum disorder.
Comprehensive profiling of anaesthetised brain dynamics across phylogeny
Protocol for the induction of human spinal motor neurons from human induced pluripotent stem cells for studying amyotrophic lateral sclerosis.
Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome.
Experimental basis for generating nonhuman primate models of frontotemporal dementia and Alzheimer's disease.
Statin use and risk of amyotrophic lateral sclerosis: An active-comparator, new-user cohort study
Neurofilament Light Chain as a Key Predictor of Cognitive Function and Mortality in Centenarians: A Study of Plasma Neural Biomarkers in Aging
Functional connectivity, structural connectivity, and inter-individual variability in <i>Drosophila melanogaster</i>
Cerebrospinal fluid extracellular vesicle-derived miR-9-3p in spinal cord injury with neuroprotective implications and biomarker development.
Spinal cord motor neuron phenotypes and polygenic risk scores in sporadic amyotrophic lateral sclerosis: deciphering the disease pathology and therapeutic potential of ropinirole hydrochloride.
A genome-wide association study identifies the GPM6A locus associated with age at onset in ALS.
Early pathogenesis of spinal and bulbar muscular atrophy uncovered by human iPSC-derived motor neurons highlights pathogenic neuropeptides as therapeutic targets
Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster
Association of centenarian polygenic score with disability-free survival and its modification effects on aging outcomes
Design-of-Experiments for Nonlinear, Multivariate Biology: Rethinking Experimental Design through Perturb-seq
A framework for neural organoids, assembloids and transplantation studies