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Jennifer A. Lacap

Gene Therapy Laboratory · FR
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Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Hippo signaling pathway, Cell biology, Cancer research, Biology, Ubiquitin, and KRAS.
h-index
citations
915
works
10
NIH funding
primary concept
email

Recent publications

Cooperation between the Hippo and MAPK pathway activation drives acquired resistance to TEAD inhibition
Nature Communications 2025cited by 21position: middledoi
RIT1M90I Is a Driver of Lung Adenocarcinoma Tumorigenesis and Resistance to Targeted Therapy
Cancer Research 2025cited by 0position: middledoi
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
eLife 2024cited by 2position: middledoi
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
eLife 2024cited by 2position: middledoi
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
eLife 2024cited by 1position: middledoi
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
Nature Cancer 2023cited by 188position: middledoi
Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
Cell Reports 2020cited by 171position: middledoi
Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer
Clinical Cancer Research 2017cited by 282position: middledoi
KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer
Cell 2017cited by 184position: middledoi
Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis
Breast Cancer Research and Treatment 2017cited by 64position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Lisa Crocker · Indiana University – Purdue University Indianapolis2 papers (2017–2017)Deepak Sampath · Amgen (United States)2 papers (2017–2017)Amy Young · American Board of Internal Medicine2 papers (2017–2017) · 2 papers (2025–2025) · 1 papers (2025–2025)Anwesha Dey · Gene Therapy Laboratory1 papers (2025–2025)Ros Cutts · Institute of Cancer Research1 papers (2017–2017)Peter Hsu · Gene Therapy Laboratory1 papers (2025–2025) · 1 papers (2025–2025)Chris Bakal · European Bioinformatics Institute1 papers (2017–2017) · 1 papers (2025–2025) · 1 papers (2020–2020) · 1 papers (2025–2025)Kai Barck · Gene Therapy Laboratory1 papers (2025–2025)Mirunalini Ravichandran · Translational Research in Oncology1 papers (2025–2025) · 1 papers (2017–2017)James A. Mondo · University of California, Santa Barbara1 papers (2025–2025) · 1 papers (2025–2025)Zheng Zhou · Nanjing Tech University1 papers (2020–2020)Barry S. Taylor · University of Maryland, Baltimore1 papers (2017–2017)
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