Area of research
Cell Biology · Molecular Biology
Research interest
Research interests include Cell biology, Biology, Unfolded protein response, Endoplasmic reticulum, Protein biosynthesis, and Stress (linguistics).
Plasticity of the mammalian integrated stress response
Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
Phosphorylation of GCN2 by mTOR confers adaptation to conditions of hyper-mTOR activation under stress
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity
Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation
Adaptation to mitochondrial stress requires CHOP-directed tuning of ISR
The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer
Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
A Unique ISR Program Determines Cellular Responses to Chronic Stress
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer
The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health
Angiogenin-Cleaved tRNA Halves Interact with Cytochrome <i>c</i>, Protecting Cells from Apoptosis during Osmotic Stress
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
A Self-defeating Anabolic Program Leads to β-Cell Apoptosis in Endoplasmic Reticulum Stress-induced Diabetes via Regulation of Amino Acid Flux
Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress