Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research interests include Melanoma and MAPK Pathways, Cancer Mechanisms and Therapy, Protein Kinase Regulation and GTPase Signaling, and RNA modifications and cancer.
Nonmonotone invasion landscape by noise-aware control of metastasis activator levels
Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses
SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells
Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop
New strategies for targeting kinase networks in cancer
Tumor Extracellular Vesicles Regulate Macrophage-Driven Metastasis through CCL5
Limited inhibition of multiple nodes in a driver network blocks metastasis
Observation and Control of Gene Expression Noise: Barrier Crossing Analogies Between Drug Resistance and Metastasis
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism
Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer
Targeting Raf Kinase Inhibitory Protein Regulation and Function
Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome
Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages
Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions
Raf Kinase Inhibitory Protein (RKIP) as a Metastasis Suppressor: Regulation of Signaling Networks in Cancer
RKIP Structure Drives Its Function: A Three-State Model for Regulation of RKIP
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis
Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells
RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2
RKIP Inhibition in Cervical Cancer Is Associated with Higher Tumor Aggressive Behavior and Resistance to Cisplatin Therapy
A Prognostic Gene Signature for Metastasis-Free Survival of Triple Negative Breast Cancer Patients
An integrated view of cyclin E function and regulation
Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer
Downregulation of RKIP Is Associated with Poor Outcome and Malignant Progression in Gliomas
Identification of novel metastasis suppressor signaling pathways for breast cancer