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Alexander M. Frankell

University of Cambridge · GB
Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, RNA modifications and cancer, and Lung Cancer Diagnosis and Treatment.
h-index
19
citations
3,400
works
78
NIH funding
primary concept
Medicine
email

Recent publications

Integrated epidemiological and molecular data inform the relationship between precancer and cancer states of esophageal adenocarcinoma
Nature Medicine 2026cited by 2position: middledoi
ctDNA monitoring using tumor-informed copy number analysis
EMBO Molecular Medicine 2026cited by 0position: middledoi
Abstract 1128: Personalized cell-free DNA fragmentation dynamics in early-stage NSCLC in TRACERx
Cancer Research 2026cited by 0position: middledoi
Abstract LB413: Peripheral blood as the sole source for cancer neoantigen and reactive T cell discovery
Cancer Research 2026cited by 0position: middledoi
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma
Nature Cancer 2025cited by 12position: middledoi
Clone copy number diversity is linked to survival in lung cancer
Nature 2025cited by 4position: middledoi
Somatic evolution following cancer treatment in normal tissue
Nature 2025cited by 3position: middledoi
Integrated epidemiogical and genomic data yields insights into the relationship between precancer and cancer states of the oesophagus
Research Square 2025cited by 0position: middledoi
152P Association of genetic intra-tumour heterogeneity with outcome in TRACERx
Annals of Oncology 2025cited by 0position: middledoi
3012MO Metastasis dissemination and divergence timing in TRACERx
Annals of Oncology 2025cited by 0position: middledoi
1909P Radiological and molecular patterns of metastatic growth in lung cancer within TRACERx
Annals of Oncology 2025cited by 0position: middledoi
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
Nature Communications 2024cited by 42position: middledoi
Abstract PR011: Comprehensive longitudinal tracking of lung cancer evolutionary clonal dynamics during therapy using circulating tumour DNA
Cancer Research 2024cited by 0position: firstdoi
LBA9 Clinical insights from ultra-sensitive tumour-informed ctDNA tracking across the TRACERx cohort
Annals of Oncology 2024cited by 0position: middledoi
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
Nature 2023cited by 327position: middledoi
The evolution of lung cancer and impact of subclonal selection in TRACERx
Nature 2023cited by 300position: firstdoi
RETRACTED ARTICLE: Antibodies against endogenous retroviruses promote lung cancer immunotherapy
Nature 2023cited by 247position: middledoi
The evolution of non-small cell lung cancer metastases in TRACERx
Nature 2023cited by 230position: middledoi
Body composition and lung cancer-associated cachexia in TRACERx
Nature Medicine 2023cited by 123position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Nicholas McGranahan · London Cancer5 papers (2024–2025)Charles Swanton · Cancer Evolution and Genome Instability Laboratory4 papers (2024–2025)Mariam Jamal‐Hanjani · CRUK Lung Cancer Centre of Excellence3 papers (2024–2025)Selvaraju Veeriah · University College London Hospitals NHS Foundation Trust3 papers (2024–2025)Carlos Martínez‐Ruiz · The Francis Crick Institute3 papers (2025–2025) · 3 papers (2024–2025) · 3 papers (2025–2025)Simone Zaccaria · University of Illinois Urbana-Champaign3 papers (2025–2025)James R. Black · Department of Health and Human Services3 papers (2024–2025)Aino‐Maija Leppä · The Francis Crick Institute2 papers (2025–2025) · 2 papers (2025–2025)Amedeo A. Azizi · Vienna General Hospital2 papers (2025–2025) · 2 papers (2025–2025)Kristiana Grigoriadis · The Francis Crick Institute2 papers (2024–2025) · 2 papers (2025–2025)Ariana Huebner · The Francis Crick Institute2 papers (2025–2025)Woody Z Zhang · Cancer Research UK2 papers (2026–2026)W.K. Liu · Nanchang University2 papers (2024–2025)Kerstin Haase · German Cancer Society2 papers (2025–2025)Emma Hazelwood · Cancer Research UK Cambridge Center2 papers (2025–2025)