Area of research
Molecular Biology · Oncology
Research interest
Research interests include Hedgehog Signaling Pathway Studies, Chemokine receptors and signaling, Epigenetics and DNA Methylation, and Cytokine Signaling Pathways and Interactions.
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction
Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits
KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion
Smoothened stimulation by membrane sterols drives Hedgehog pathway activity
HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β
Co-Expression of VEGF and IL-6 Family Cytokines is Associated with Decreased Survival in HER2 Negative Breast Cancer Patients: Subtype-Specific IL-6 Family Cytokine-Mediated VEGF Secretion