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Wen-Jen Hwu

The University of Texas MD Anderson Cancer Center · US
Area of research
Oncology · Molecular Biology
Research interest
Research interests include Cutaneous Melanoma Detection and Management, Melanoma and MAPK Pathways, Cancer Immunotherapy and Biomarkers, and Immunotherapy and Immune Responses.
h-index
45
citations
30,875
works
99
NIH funding
primary concept
Medicine
email

Recent publications

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
Nature Medicine 2021cited by 405position: middledoi
Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma
European Journal of Cancer 2020cited by 98position: middledoi
High response rate to PD-1 blockade in desmoplastic melanomas
Nature 2018cited by 331position: middledoi
Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab
Clinical Cancer Research 2018cited by 306position: middledoi
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors
JCI Insight 2018cited by 147position: middledoi
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
Science 2017cited by 4,620position: middledoi
Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab
Cell 2017cited by 2,538position: middledoi
Standard-dose pembrolizumab in combination with reduced-dose ipilimumab for patients with advanced melanoma (KEYNOTE-029): an open-label, phase 1b trial
The Lancet Oncology 2017cited by 246position: middledoi
Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma
JAMA 2016cited by 1,059position: middledoi
Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade
Cancer Discovery 2016cited by 1,006position: middledoi
Long term survival with cytotoxic T lymphocyte-associated antigen 4 blockade using tremelimumab
European Journal of Cancer 2015cited by 83position: middledoi
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
The Lancet 2014cited by 1,759position: middledoi
Treatment of BRAF-mutated advanced cutaneous melanoma.
PubMed 2014cited by 10position: lastdoi
Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma
New England Journal of Medicine 2013cited by 3,390position: middledoi
Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
New England Journal of Medicine 2012cited by 7,974position: middledoi
The Role of Alpha-Synuclein in Melanin Synthesis in Melanoma and Dopaminergic Neuronal Cells
PLoS ONE 2012cited by 118position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Antoni Ribas · UCLA Medical Center6 papers (2014–2020)F. Stephen Hodi · Harvard University5 papers (2014–2020)Richard W. Joseph · The University of Texas Southwestern Medical Center4 papers (2014–2020)Bartosz Chmielowski · UCLA Medical Center3 papers (2014–2018)Jeffrey S. Weber · Heinrich Heine University Düsseldorf3 papers (2014–2020)Jedd D. Wolchok · Cornell University3 papers (2014–2020)Richard Kefford · Macquarie University3 papers (2014–2018)Georgina V. Long · ARC Centre of Excellence in Synthetic Biology3 papers (2017–2020)Matteo S. Carlino · Mater Health Services3 papers (2017–2020)Anthony M. Joshua · Garvan Institute of Medical Research3 papers (2014–2020)Caroline Robert · Institut Gustave Roussy3 papers (2014–2020) · 3 papers (2014–2018)Adil Daud · UCSF Helen Diller Family Comprehensive Cancer Center3 papers (2014–2020)Roxana Dronca · University of Rochester Medical Center3 papers (2014–2020)Omid Hamid · University Hospital Münster3 papers (2014–2020)Nageatte Ibrahim · Merck & Co., Inc., Rahway, NJ, USA (United States)2 papers (2017–2020)Benjamin Y. Kong · The University of Sydney2 papers (2017–2018)Peter Hersey · University of Sydney2 papers (2018–2020)Amita Patnaik · South Texas Accelerated Research Therapeutics2 papers (2014–2018)Xiaoyan Wang · Xuzhou Medical College2 papers (2015–2018)