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Xinan Sheng

Peking University · CN
Area of research
Oncology · Surgery
Research interest
Research interests include Bladder and Urothelial Cancer Treatments, Cutaneous Melanoma Detection and Management, Cancer Immunotherapy and Biomarkers, and Melanoma and MAPK Pathways.
h-index
41
citations
6,845
works
437
NIH funding
primary concept
Medicine
email

Recent publications

Disitamab vedotin with or without PD-1 inhibitors in pretreated patients with locally advanced or metastatic urothelial carcinoma: Identifying patients who derive additional benefit from immune combination therapy
Urologic Oncology: Seminars and Original Investigations 2026cited by 2position: contributordoi
Toripalimab in patients with previously treated advanced upper tract urothelial carcinoma: a subgroup analysis of the phase II POLARIS-03 trial.
2026cited by 0position: contributordoi
A phase II peri-operative study of pembrolizumab plus lenvatinib for mucosal melanoma.
2026cited by 0position: contributordoi
Disitamab Vedotin plus Toripalimab in HER2-Expressing Advanced Urothelial Cancer
New England Journal of Medicine 2025cited by 39position: firstdoi
Disitamab vedotin plus toripalimab in patients with locally advanced or metastatic urothelial carcinoma (RC48-C014): a phase Ib/II dose-escalation and dose-expansion study.
2025cited by 34position: contributordoi
Disitamab Vedotin plus Toripalimab in HER2-Expressing Advanced Urothelial Cancer.
2025cited by 19position: contributordoi
Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights.
2025cited by 14position: contributordoi
Efficacy and safety of DV in HER2-negative and HER2-low locally advanced or metastatic urothelial carcinoma: Results of a phase 2 study.
2025cited by 10position: contributordoi
First-line benmelstobart plus anlotinib versus sunitinib in advanced renal cell carcinoma (ETER100): a multicentre, randomised, open-label, phase 3 trial
The Lancet Oncology 2025cited by 9position: lastdoi
Nectin-4 targeted ADC, SHR-A2102, in patients with advanced or metastatic urothelial carcinoma: A phase 1 study.
Journal of Clinical Oncology 2025cited by 8position: middledoi
Comprehensive molecular profiling of FH-deficient renal cell carcinoma identifies molecular subtypes and potential therapeutic targets.
2025cited by 7position: contributordoi
Neoadjuvant toripalimab plus nimotuzumab combined with taxol-based chemotherapy in locally advanced penile squamous cell carcinoma.
2025cited by 6position: contributordoi
First-line benmelstobart plus anlotinib versus sunitinib in advanced renal cell carcinoma (ETER100): a multicentre, randomised, open-label, phase 3 trial.
2025cited by 5position: contributordoi
Genomic characterization reveals distinct mutational landscape of acral melanoma in East Asian.
2025cited by 3position: contributordoi
Sintilimab Plus Axitinib for Advanced Fumarate Hydratase-Deficient Renal Cell Carcinoma: A Phase 2 Nonrandomized Clinical Trial.
2025cited by 2position: contributordoi
MARCO+ Tumor-Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma.
2025cited by 2position: contributordoi
Phase Ib study of anti-PD-L1 monoclonal antibody socazolimab in combination with nab-paclitaxel as first-line therapy for advanced urothelial carcinoma.
2025cited by 2position: contributordoi
Predominance of hyperprogression in mucosal melanoma during anti-PD-1 monotherapy treatment.
2025cited by 2position: contributordoi
Real-World Efficacy and Safety of Anti-PD-1 Antibody Plus Apatinib and Temozolomide for Advanced Acral Melanoma.
2025cited by 1position: contributordoi
Dynamic Change of PD-L2 on Circulating Plasma Extracellular Vesicles as a Predictor of Treatment Response in Melanoma Patients Receiving Anti-PD-1 Therapy.
2025cited by 1position: contributordoi
Advances in antibody-drug conjugates for urothelial carcinoma treatment.
2025cited by 0position: contributordoi
Systematic profiling of tumor-associated antigen expression for antibody-drug conjugate in prostate cancer.
2025cited by 0position: contributordoi
Clinical Characteristics and Impact on Prognosis of Melanoma Accompanied by Multiple Primary Malignancies: A Retrospective Analysis.
2025cited by 0position: contributordoi
A prognostic model for survival of patients with metastatic upper tract urothelial carcinoma with first-line systemic therapy.
2025cited by 0position: contributordoi
Supplementary Video S1 from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
2025cited by 0position: contributordoi
Supplementary Figures S1-S15 from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
2025cited by 0position: contributordoi
Supplementary Methods S1 from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
2025cited by 0position: contributordoi
Supplementary Video S2A from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
2025cited by 0position: contributordoi
Supplementary Video S2B from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
2025cited by 0position: contributordoi
Supplementary Table S3 from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma
2025cited by 0position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 120 papers (2021–2026)Xing Yang · Nanjing Tech University75 papers (2023–2025)Martin G. Pomper · Institute for Advanced Journalism Studies75 papers (2023–2025)Steven P. Rowe · St Vincents Institute of Medical Research75 papers (2023–2025)Ning Zhang · Shaoxing University75 papers (2023–2025) · 75 papers (2023–2025) · 75 papers (2023–2025) · 75 papers (2023–2025)Nan Li · Peking University75 papers (2023–2025)Xiaojiang Duan · Peking University75 papers (2023–2025)Lei Xia · Chinese Academy of Social Sciences75 papers (2023–2025)Xuesong Li · Ningxia Normal University75 papers (2023–2025)Zhi Yang · China Institute of Atomic Energy75 papers (2023–2025) · 75 papers (2023–2025)Hua Zhu · Guizhou University75 papers (2023–2025)Yanan Ren · Hefei University of Technology75 papers (2023–2025)Zhuochen Zhang · Peking University75 papers (2023–2025) · 20 papers (2021–2025)Jun Guo · Hebei Medical University14 papers (2013–2024)Patricia Keegan · Columbia University Irving Medical Center12 papers (2021–2023)