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Guillaume Médard

Technical University of Munich · DE
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Area of research
Cellular and Molecular Neuroscience · Computational Theory and Mathematics
Research interest
Research interests include Chemistry, Drug discovery, Kinome, Kinase, Computational biology, and Biochemistry.
h-index
citations
1,608
works
16
NIH funding
primary concept
email

Recent publications

Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors
Nature Chemical Biology 2023cited by 81position: middledoi
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid
Nature Communications 2023cited by 27position: middledoi
Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target
Nature Chemical Biology 2022cited by 110position: lastdoi
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
Journal of the American Chemical Society 2022cited by 41position: middledoi
Author Correction: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target
Nature Chemical Biology 2022cited by 1position: lastdoi
Aza-SAHA Derivatives are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
ChemRxiv 2022cited by 1position: middledoi
Chemoproteomic Selectivity Profiling of PIKK and PI3K Kinase Inhibitors
ACS Chemical Biology 2019cited by 40position: lastdoi
Kinobeads: A Chemical Proteomic Approach for Kinase Inhibitor Selectivity Profiling and Target Discovery
Methods and principles in medicinal chemistry 2019cited by 22position: middledoi
NVP‐BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family
ChemMedChem 2018cited by 27position: middledoi
The target landscape of clinical kinase drugs
Science 2017cited by 864position: middledoi
Chemoproteomics‐Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors
ChemMedChem 2017cited by 32position: lastdoi
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors
ACS Chemical Biology 2016cited by 110position: middledoi
Chemical Proteomics and Structural Biology Define EPHA2 Inhibition by Clinical Kinase Drugs
ACS Chemical Biology 2016cited by 56position: middledoi
Optimized Chemical Proteomics Assay for Kinase Inhibitor Profiling
Journal of Proteome Research 2015cited by 136position: firstdoi
Evaluation of Kinase Activity Profiling Using Chemical Proteomics
ACS Chemical Biology 2015cited by 38position: middledoi
New Affinity Probe Targeting VEGF Receptors for Kinase Inhibitor Selectivity Profiling by Chemical Proteomics
Journal of Proteome Research 2014cited by 22position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Bernhard Küster · German Cancer Research Center15 papers (2014–2023)Stephanie Heinzlmeir · Technical University of Munich9 papers (2014–2019)Mathias Wilhelm · Texas Instruments (Germany)7 papers (2015–2023)Raphael R. Steimbach · German Cancer Research Center5 papers (2022–2023)Severin Lechner · Technical University of Munich5 papers (2022–2023)Aubry K. Miller · German Cancer Research Center5 papers (2022–2023)Benjamin Ruprecht · Technical University of Munich4 papers (2015–2019)Xin Ku · Technical University of Munich4 papers (2014–2022)Dominic Helm · The University of Texas MD Anderson Cancer Center4 papers (2014–2016)Susan Klaeger · Broad Institute4 papers (2015–2019)Huichao Qiao · Technical University of Munich3 papers (2015–2016)D. Kudlinzki · Goethe University Frankfurt3 papers (2016–2018)V.L. Linhard · Goethe University Frankfurt3 papers (2016–2018)Sridhar Sreeramulu · Goethe University Frankfurt3 papers (2016–2018)S.L. Gande · Goethe University Frankfurt3 papers (2016–2018)Maria Reinecke · Technical University of Munich3 papers (2019–2023)Karl Kramer · Technical University of Munich3 papers (2015–2022)Krishna Saxena · MRB Research Center for Magnetic Resonance Bavaria3 papers (2016–2018)Harald Schwalbe · Goethe University Frankfurt3 papers (2016–2018)Gernot Poschet · European Molecular Biology Organization2 papers (2022–2022)
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