Area of research
Molecular Biology · Oncology
Research interest
Research interests include DNA Repair Mechanisms, PARP inhibition in cancer therapy, Cancer-related Molecular Pathways, and CRISPR and Genetic Engineering.
IgG is an aging factor that drives adipose tissue fibrosis and metabolic decline
Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
The Mechanism, Regulation and Evolution of V(D)J Recombination
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion
Author Correction: Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization
Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization
PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells
MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining
Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL
Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination
Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM
Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency
Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining
Ataxia Telangiectasia Mutated (ATM) Is Dispensable for Endonuclease I-SceI-induced Homologous Recombination in Mouse Embryonic Stem Cells
Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)