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Scott J. Hultgren

Washington University in St. Louis · US
Area of research
Endocrinology · Epidemiology
Research interest
Research interests include Escherichia coli research studies, Urinary Tract Infections Management, Bacterial Genetics and Biotechnology, and Gut microbiota and health.
h-index
118
citations
46,401
works
411
NIH funding
primary concept
email

Recent publications

Case report: Long-term follow-up of patients who received a FimCH vaccine for prevention of recurrent urinary tract infections caused by antibiotic resistant Enterobacteriaceae: a case report series
Frontiers in Immunology 2024cited by 10position: middledoi
Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome
Nature Microbiology 2023cited by 62position: lastdoi
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women
Nature Microbiology 2022cited by 174position: middledoi
Bacterial virulence phenotypes of <i>Escherichia coli</i> and host susceptibility determine risk for urinary tract infections
Science Translational Medicine 2017cited by 163position: lastdoi
A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease
Nature Microbiology 2016cited by 101position: lastdoi
Urinary tract infections: epidemiology, mechanisms of infection and treatment options
Nature Reviews Microbiology 2015cited by 4,093position: lastdoi
Human Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli
mBio 2015cited by 78position: lastdoi
Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection
PLoS Pathogens 2015cited by 71position: middledoi
Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis
EBioMedicine 2014cited by 115position: lastdoi
Pilicide ec240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli
mBio 2014cited by 76position: lastdoi
Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation
Proceedings of the National Academy of Sciences 2013cited by 155position: lastdoi
Genomic Diversity and Fitness of <i>E. coli</i> Strains Recovered from the Intestinal and Urinary Tracts of Women with Recurrent Urinary Tract Infection
Science Translational Medicine 2013cited by 151position: middledoi
Structural and energetic basis of folded-protein transport by the FimD usher
Nature 2013cited by 99position: middledoi
From Physiology to Pharmacy: Developments in the Pathogenesis and Treatment of Recurrent Urinary Tract Infections
Current Urology Reports 2013cited by 94position: lastdoi
Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in <i>Enterococcus faecalis</i>
Proceedings of the National Academy of Sciences 2013cited by 86position: middledoi
Pilin and Sortase Residues Critical for Endocarditis- and Biofilm-Associated Pilus Biogenesis in Enterococcus faecalis
Journal of Bacteriology 2013cited by 83position: lastdoi
Estrogen and Recurrent UTI: What Are the Facts?
Science Translational Medicine 2013cited by 21position: lastdoi
Host–pathogen checkpoints and population bottlenecks in persistent and intracellular uropathogenic<i>Escherichia coli</i>bladder infection
FEMS Microbiology Reviews 2012cited by 345position: lastdoi
The Metal Ion-Dependent Adhesion Site Motif of the Enterococcus faecalis EbpA Pilin Mediates Pilus Function in Catheter-Associated Urinary Tract Infection
mBio 2012cited by 153position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

· 8 papers (2012–2023)Thomas M. Hooton · University of Miami7 papers (2013–2024)Jerome S. Pinkner · The University of Texas Health Science Center at Houston5 papers (2012–2022)Michael G. Caparon · Institute for Women's Policy Research4 papers (2012–2015) · 4 papers (2013–2022)Jonathan Livny · Broad Institute4 papers (2014–2023)Marco Colonna · BJC HealthCare3 papers (2014–2023)Henry L. Schreiber · Massachusetts Institute of Technology3 papers (2013–2022)Michael E. Hibbing · Indiana University Bloomington3 papers (2013–2017)Kimberly A. Kline · The University of Texas at Austin3 papers (2012–2013)Swaine L. Chen · National University of Singapore3 papers (2013–2015)Staffan Normark · Karolinska University Hospital3 papers (2012–2013)Andrew L. Kau · Washington University in St. Louis3 papers (2013–2024)Birgitta Henriques‐Normark · Karolinska University Hospital3 papers (2012–2013)Ann E. Stapleton · Seattle University2 papers (2014–2017)Valerie P. O’Brien · University of California Davis Medical Center2 papers (2016–2023)Thaddeus S. Stappenbeck · Cleveland Clinic2 papers (2014–2023)Hailyn V. Nielsen · University of California, San Francisco2 papers (2012–2013)Benjamin Olson · Medical College of Wisconsin2 papers (2022–2023)Matt S. Conover · Wake Forest University2 papers (2014–2017)