Area of research
Public Health, Environmental and Occupational Health · Immunology
Research interest
Research interests include Research on Leishmaniasis Studies, Monoclonal and Polyclonal Antibodies Research, T-cell and B-cell Immunology, and Trypanosoma species research and implications.
p1/s1, a 3'-nucleotidase/nuclease, allows Leishmania major to circumvent host innate immune response mechanisms.
The Tailored Biosimilar Approach: Expectations and Requirements
p1/s1, a 3’-nucleotidase/nuclease, allows <i>Leishmania major</i> to circumvent host innate immune response mechanisms
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution
Investigating pyroptosis as a mechanism of L. major cell-to-cell spread in the human BLaER1 infection model.
Leishmania major drives host phagocyte death and cell-to-cell transfer depending on intracellular pathogen proliferation rate
Investigating pyroptosis as a mechanism of <i>L. major</i> cell‐to‐cell spread in the human <scp>BLaER1</scp> infection model
Using BLaER1 as model for L. major infection of human macrophages to investigate the role of pyroptosis in parasite spreading
The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies
Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response
Distinct single-component adjuvants steer human DC-mediated T-cell polarization via Toll-like receptor signaling toward a potent antiviral immune response.
The Flagellin:Allergen Fusion Protein rFlaA:Betv1 Induces a MyD88− and MAPK-Dependent Activation of Glucose Metabolism in Macrophages
Human monocyte-derived type 1 and 2 macrophages recognize Ara h 1, a major peanut allergen, by different mechanisms
Enhanced activation of blood neutrophils and monocytes in patients with Ethiopian localized cutaneous leishmaniasis in response to Leishmania aethiopica Neutrophil activation in Ethiopian cutaneous leishmaniasis
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.
Enhanced production of pro-inflammatory cytokines and chemokines in Ethiopian cutaneous leishmaniasis upon exposure to Leishmania aethiopica
HIF1A and NFAT5 coordinate Na<sup>+</sup>-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting
Cathelicidin Contributes to the Restriction of Leishmania in Human Host Macrophages
Anti-Tumor Necrosis Factor α Therapeutics Differentially Affect Leishmania Infection of Human Macrophages
Dectin-1 Positive Dendritic Cells Expand after Infection with Leishmania major Parasites and Represent Promising Targets for Vaccine Development
LC3-associated phagocytosis in microbial pathogenesis
Nivolumab Enhances In Vitro Effector Functions of PD-1+ T-Lymphocytes and Leishmania-Infected Human Myeloid Cells in a Host Cell-Dependent Manner
In vitro permissiveness of bovine neutrophils and monocyte derived macrophages to Leishmania donovani of Ethiopian isolate
Apoptotic-like<i>Leishmania</i>exploit the host´s autophagy machinery to reduce T-cell-mediated parasite elimination
An Emerging Approach for Parallel Quantification of Intracellular Protozoan Parasites and Host Cell Characterization Using TissueFAXS Cytometry
Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of <i>Mycobacterium tuberculosis</i> in Human Macrophages