Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Chemistry, Conotoxin, Nicotinic agonist, Acetylcholine receptor, Pharmacology, and Nicotinic acetylcholine receptor.
Recent Advances in Drug Development for Alzheimer’s Disease: A Comprehensive Review
Synthesis of the plant cyclotide cyO14 via the hydrazide strategy and investigation of its antibacterial and insecticidal activities
α6 nicotinic acetylcholine receptors: A pharmacological challenge with untapped therapeutic promise
The Metabolic Regulation of the NKG2D-Positive NK and T Cells and Their Role in Disease Progression
α9 Nicotinic Acetylcholine Receptor Promotes Tumor Proliferation and Suppresses Ferroptosis in Triple-Negative Breast Cancer
Synthesis of Cyclic Hexapeptides via the Hydrazide Method and Evaluation of Their Antibacterial Activities
αO-Conotoxin GeXIVA[1,2] Suppresses In Vivo Tumor Growth of Triple-Negative Breast Cancer by Inhibiting AKT-mTOR, STAT3 and NF-κB Signaling Mediated Proliferation and Inducing Apoptosis
αO-Conotoxin GeXIVA[1,2] Reduced Neuropathic Pain and Changed Gene Expression in Chronic Oxaliplatin-Induced Neuropathy Mice Model
Fatty acid chain modification enhances the serum stability of antimicrobial peptide B1 and activities against Staphylococcus aureus and Klebsiella pneumoniae
Integrative transcriptome and mass spectrometry analysis reveals novel cyclotides with antimicrobial and cytotoxic activities from Viola arcuata
Engineering Enhanced Antimicrobial Properties in α-Conotoxin RgIA through D-Type Amino Acid Substitution and Incorporation of Lysine and Leucine Residues
Fluorescent α-Conotoxin [Q1G, ΔR14]LvIB Identifies the Distribution of α7 Nicotinic Acetylcholine Receptor in the Rat Brain
Loop2 Size Modification Reveals Significant Impacts on the Potency of α-Conotoxin TxID
Development of sertraline analogues as potential anti-ischemic stroke agents
Synthesis of the Most Potent Isomer of μ-Conotoxin KIIIA Using Different Strategies
Peptides from the Sea Anemone Metridium senile with Modified Inhibitor Cystine Knot (ICK) Fold Inhibit Nicotinic Acetylcholine Receptors
Inflammation Regulation via an Agonist and Antagonists of α7 Nicotinic Acetylcholine Receptors in RAW264.7 Macrophages
Anti-Ovarian Cancer Conotoxins Identified from Conus Venom
Fluorescently Labeled α-Conotoxin TxID, a New Probe for α3β4 Neuronal Nicotinic Acetylcholine Receptors
α-Conotoxin TxIB Improved Behavioral Abnormality and Changed Gene Expression in Zebrafish (Danio rerio) Induced by Alcohol Withdrawal
Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment
Isolation and characterization of five novel disulfide-poor conopeptides from Conus marmoreus venom
Characterization of an α 4/7-Conotoxin LvIF from Conus lividus That Selectively Blocks α3β2 Nicotinic Acetylcholine Receptor
Cysteine [2,4] Disulfide Bond as a New Modifiable Site of α-Conotoxin TxIB
α-Conotoxin TxIB Inhibits Development of Morphine-Induced Conditioned Place Preference in Mice via Blocking α6β2* Nicotinic Acetylcholine Receptors
From Crystal Structures of RgIA4 in Complex with Ac-AChBP to Molecular Determinants of Its High Potency of α9α10 nAChR
αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors
Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB
α-Conotoxin TxID and [S9K]TxID, α3β4 nAChR Antagonists, Attenuate Expression and Reinstatement of Nicotine-Induced Conditioned Place Preference in Mice