Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Parkinson's Disease Mechanisms and Treatments, Amyotrophic Lateral Sclerosis Research, and Dementia and Cognitive Impairment Research.
Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study
Genome sequence analyses identify novel risk loci for multiple system atrophy
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
Association of biological sex with clinical outcomes and biomarkers of Alzheimer’s disease in adults with Down syndrome
Embracing Monogenic Parkinson's Disease: The <scp>MJFF</scp> Global Genetic <scp>PD</scp> Cohort
Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by <i>HLA-DRB1*04</i> subtypes
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease
Association of Rare <i>APOE</i> Missense Variants V236E and R251G With Risk of Alzheimer Disease
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood
Protective association of <i>HLA‐DRB1</i>*04 subtypes in neurodegenerative diseases implicates acetylated tau PHF6 sequences
Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer’s disease in adults with Down syndrome
Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve
Use of plasma biomarkers for AT(N) classification of neurodegenerative dementias
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
The <i>MS4A</i> gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk
Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
Cortical microstructure in the behavioural variant of frontotemporal dementia: looking beyond atrophy
Heritability and genetic variance of dementia with Lewy bodies
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia
Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
CXCR4 involvement in neurodegenerative diseases