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Haihua Xiao

Massachusetts Institute of Technology · US
Area of research
Biomedical Engineering · Biomaterials
Research interest
Research interests include Cancer research, Materials science, Reactive oxygen species, Cisplatin, Chemistry, and Nanoparticle.
h-index
citations
2,791
works
26
NIH funding
primary concept
email

Recent publications

Ultrasound‐Triggered Nanoparticles Induce Cuproptosis for Enhancing Immunogenic Sonodynamic Therapy
Advanced Materials 2025cited by 24position: middledoi
Reprogramming mitochondrial metabolism to enhance macrophages polarization by ROS-responsive nanoparticles for osteoarthritis
Biomaterials 2025cited by 21position: middledoi
Iron‐Chelating and ROS‐Scavenging Polymers with Thioketal and Thioether Bonds Delivering Ferroptosis Inhibitor Lip‐1 Provide a Triple Therapeutic Strategy for Retina Ganglion Cells in Acute Glaucoma
Advanced Materials 2025cited by 17position: middledoi
Nanotheranostics with Radionuclides for Cancer Diagnosis and Therapy
Advanced Functional Materials 2025cited by 15position: middledoi
PSMA‐Targeted Nanoparticles with PI3K/mTOR Dual Inhibitor Downregulate P‐Glycoprotein and Inactivate Myeloid‐Derived Suppressor Cells for Enhanced Chemotherapy and Immunotherapy in Prostate Cancer
Advanced Materials 2025cited by 11position: middledoi
NIR‐II Photoactivatable Cobalt(III) Nanoparticles for Photoactivated Metal Chemo‐Immunotherapy
Advanced Materials 2025cited by 6position: middledoi
A Novel Zinc(II) Complex for Sonodynamic Therapy Induces Pyroptosis of Breast Cancer Cells and Enhances Anti‐Tumor Immune Response
Advanced Science 2025cited by 5position: middledoi
Near Infrared‐Fluorescent Dinuclear Iridium(III) Nanoparticles for Immunogenic Sonodynamic Therapy
Advanced Materials 2024cited by 45position: middledoi
Activating CD8<sup>+</sup> T Cells by Pt(IV) Prodrug‐Based Nanomedicine and aPD‐L1 Antibody for Enhanced Cancer Immunotherapy
Advanced Materials 2024cited by 36position: lastdoi
NIR‐II Fluorescent Nanotheranostics with a Switchable Irradiation Mode for Immunogenic Sonodynamic Therapy
Advanced Materials 2024cited by 26position: lastdoi
Cuproptosis Induced by ROS Responsive Nanoparticles with Elesclomol and Copper Combined with αPD‐L1 for Enhanced Cancer Immunotherapy
Advanced Materials 2023cited by 379position: middledoi
Targeting DNA Damage and Repair Machinery via Delivering WEE1 Inhibitor and Platinum (IV) Prodrugs to Stimulate STING Pathway for Maximizing Chemo‐Immunotherapy in Bladder Cancer
Advanced Materials 2023cited by 64position: middledoi
Hepatocyte-confined CRISPR/Cas9-based nanocleaver precisely eliminates viral DNA for efficient and safe treatment of hepatitis B virus infection
Nano Today 2023cited by 26position: middledoi
A method for demand-accurate one-dimensional cutting problems with pattern reduction
Mathematical Biosciences & Engineering 2023cited by 0position: firstdoi
Photo‐Reduction with NIR Light of Nucleus‐Targeting Pt <sup>IV</sup> Nanoparticles for Combined Tumor‐Targeted Chemotherapy and Photodynamic Immunotherapy
Angewandte Chemie International Edition 2022cited by 183position: lastdoi
Biodegradable Polymer with Effective Near‐Infrared‐II Absorption as a Photothermal Agent for Deep Tumor Therapy
Advanced Materials 2021cited by 181position: lastdoi
Breaking the Intracellular Redox Balance with Diselenium Nanoparticles for Maximizing Chemotherapy Efficacy on Patient-Derived Xenograft Models
ACS Nano 2020cited by 173position: lastdoi
Microneedles loaded with anti-PD-1–cisplatin nanoparticles for synergistic cancer immuno-chemotherapy
Nanoscale 2020cited by 99position: middledoi
Cancer Cell Membrane‐Coated Nanoparticles for Personalized Therapy in Patient‐Derived Xenograft Models
Advanced Functional Materials 2019cited by 187position: middledoi
Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy
ACS Nano 2019cited by 172position: middledoi
Recent advances in delivery of photosensitive metal-based drugs
Coordination Chemistry Reviews 2019cited by 153position: middledoi
Layer‐by‐layer nanoparticles for novel delivery of cisplatin and PARP inhibitors for platinum‐based drug resistance therapy in ovarian cancer
Bioengineering & Translational Medicine 2019cited by 58position: middledoi
Fluorinated Acid‐Labile Branched Hydroxyl‐Rich Nanosystems for Flexible and Robust Delivery of Plasmids
Small 2018cited by 74position: middledoi
Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species
Nano Letters 2017cited by 652position: middledoi
A Targeted and Stable Polymeric Nanoformulation Enhances Systemic Delivery of mRNA to Tumors
Molecular Therapy 2017cited by 89position: middledoi
Maximizing Synergistic Activity When Combining RNAi and Platinum-Based Anticancer Agents
Journal of the American Chemical Society 2017cited by 80position: firstdoi
Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer
Nature Communications 2017cited by 79position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

C. F. Xu · Cells Therapy (Poland)6 papers (2024–2025)Dongsheng Tang · Michigan State University6 papers (2021–2025)Yingjie Yu · Massachusetts Institute of Technology6 papers (2017–2021) · 5 papers (2024–2025)Zheng Cao · University of California, Los Angeles4 papers (2024–2025)Ruogu Qi · Nanjing University of Chinese Medicine3 papers (2017–2017)Kun Shang · Fudan University3 papers (2025–2025)Wenkuan Wang · Chinese Academy of Medical Sciences & Peking Union Medical College3 papers (2023–2025)P. Peter Ghoroghchian · Massachusetts Institute of Technology3 papers (2017–2019)Bin Wang · Shandong University3 papers (2022–2024)Feiya Yang · Chinese Academy of Medical Sciences & Peking Union Medical College3 papers (2023–2025)Yongheng Wang · Tongji University3 papers (2017–2020)Lu Yin · Peking University Sixth Hospital3 papers (2023–2025)Haiqin Song · Massachusetts Institute of Technology3 papers (2017–2017)Hanchen Zhang · Chinese Academy of Sciences3 papers (2024–2025)Nianzeng Xing · Chinese Academy of Medical Sciences & Peking Union Medical College3 papers (2023–2025)Ganghao Liang · Chinese Academy of Sciences2 papers (2024–2025)Qixian Chen · Massachusetts Institute of Technology2 papers (2017–2017)Qi Zhang · Qilu University of Technology2 papers (2019–2021) · 2 papers (2025–2025)