Area of research
Molecular Biology · Clinical Biochemistry
Research interest
Research interests include Mitochondrial Function and Pathology, Metabolism and Genetic Disorders, Proteoglycans and glycosaminoglycans research, and ATP Synthase and ATPases Research.
ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits
Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS
Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome
Hepatic NADH reductive stress underlies common variation in metabolic traits
Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU
Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation
Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics
Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome
Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome
Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter
Mitochondrial dysfunction remodels one-carbon metabolism in human cells
Hypoxia as a therapy for mitochondrial disease
Hypoxia as a therapy for mitochondrial disease
DSpace@MIT (Massachusetts Institute of Technology) 2016cited by 3position: middle
EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex