Area of research
Physiology · Immunology
Research interest
Research interests include Asthma and respiratory diseases, IL-33, ST2, and ILC Pathways, Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis, and Respiratory and Cough-Related Research.
YAP/TAZ activity in PDGFRα-expressing alveolar fibroblasts modulates AT2 proliferation through Wnt4
POS0034 REGULATE-RA: A Phase 1 Study of CAR-T Regulatory Cells Targeting Citrullinated Proteins in Refractory Rheumatoid Arthritis: Interim Safety and Tolerability
Isoform-selective TGF-β3 inhibition for systemic sclerosis
Targeted alveolar regeneration with Frizzled-specific agonists
Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases
Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma
A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk
Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma
Cross-tissue organization of the fibroblast lineage
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell population
Molecular programs of fibrotic change in aging human lung
The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF)
Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
A randomized, placebo‐controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)
Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma
Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study
Prognostic and predictive biomarkers for patients with idiopathic pulmonary fibrosis treated with pirfenidone: post-hoc assessment of the CAPACITY and ASCEND trials
Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD)
IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma
CXCL14 is a candidate biomarker for Hedgehog signalling in idiopathic pulmonary fibrosis
Seasonal variability of severe asthma exacerbations and clinical benefit from lebrikizumab
The airway microbiome in patients with severe asthma: Associations with disease features and severity
Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK)
Stratified medicine in inflammatory disorders: From theory to practice
LATE-BREAKING ABSTRACT: Serum IL-13 is a peripheral biomarker for Type 2 asthma
Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis
A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production
Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts